STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ackAAcetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (389 aa)    
Predicted Functional Partners:
Mvan_0700
Phosphotransacetylase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family.
 
 
 0.999
acsA
Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
   
 
 0.968
Mvan_1407
PFAM: AMP-dependent synthetase and ligase; KEGG: bte:BTH_II0927 acetyl-CoA synthetase.
  
 
 0.956
Mvan_1564
PFAM: AMP-dependent synthetase and ligase; KEGG: mmc:Mmcs_4438 AMP-dependent synthetase and ligase.
  
 
 0.956
Mvan_0801
TIGRFAM: isocitrate lyase; PFAM: isocitrate lyase and phosphorylmutase; KEGG: mmc:Mmcs_0636 isocitrate lyase.
   
  
 0.946
Mvan_4109
PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; pyruvate ferredoxin/flavodoxin oxidoreductase; pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: mmc:Mmcs_4865 pyruvate:ferredoxin (flavodoxin) oxidoreductase.
 
  
 0.944
Mvan_4765
PFAM: AMP-dependent synthetase and ligase; KEGG: mmc:Mmcs_4231 AMP-dependent synthetase and ligase.
   
 
 0.932
Mvan_5157
PFAM: aldehyde dehydrogenase; KEGG: mmc:Mmcs_4578 aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
  
 
 0.929
Mvan_0105
PFAM: aldehyde dehydrogenase; KEGG: mmc:Mmcs_0090 aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
  
 
 0.925
Mvan_0240
PFAM: aldehyde dehydrogenase; KEGG: mmc:Mmcs_0217 aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
  
 
 0.925
Your Current Organism:
Mycolicibacterium vanbaalenii
NCBI taxonomy Id: 350058
Other names: M. vanbaalenii PYR-1, Mycobacterium sp. PYR-1, Mycobacterium vanbaalenii DSM 7251, Mycobacterium vanbaalenii PYR-1, Mycolicibacterium vanbaalenii DSM 7251, Mycolicibacterium vanbaalenii PYR-1
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