Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Mvan_1122KEGG: mmc:Mmcs_1478 hypothetical protein. (261 aa)    
Predicted Functional Partners:
Mvan_1123
PFAM: DSBA oxidoreductase; KEGG: mmc:Mmcs_1479 DsbA oxidoreductase.
 
     0.875
Mvan_0178
KEGG: mmc:Mmcs_0152 hypothetical protein.
  
     0.548
ftsE
Cell division ATP-binding protein FtsE; Part of the ABC transporter FtsEX involved in cellular division.
       0.474
Mvan_1915
Cell division protein FtsX; Part of the ABC transporter FtsEX involved in cellular division; Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
       0.474
smpB
SsrA-binding protein; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to [...]
       0.474
Mvan_1124
PFAM: VanW family protein; KEGG: nfa:nfa54560 hypothetical protein.
       0.471
Mvan_3001
PFAM: dihydrodipicolinate reductase; homoserine dehydrogenase, NAD-binding; KEGG: mmc:Mmcs_2712 dihydrodipicolinate reductase.
  
     0.443
Mvan_4922
PFAM: dihydrodipicolinate reductase; homoserine dehydrogenase, NAD-binding; KEGG: mpa:MAP0870c hypothetical protein.
  
     0.436
Mvan_0181
PFAM: protein of unknown function DUF58; KEGG: mmc:Mmcs_0155 protein of unknown function DUF58.
  
     0.404
Your Current Organism:
Mycolicibacterium vanbaalenii
NCBI taxonomy Id: 350058
Other names: M. vanbaalenii PYR-1, Mycobacterium sp. PYR-1, Mycobacterium vanbaalenii DSM 7251, Mycobacterium vanbaalenii PYR-1, Mycolicibacterium vanbaalenii DSM 7251, Mycolicibacterium vanbaalenii PYR-1
Server load: low (10%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.