node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Mvan_2582 | Mvan_2706 | Mvan_2582 | Mvan_2706 | TIGRFAM: preprotein translocase, YajC subunit; PFAM: YajC family protein; KEGG: mmc:Mmcs_2275 preprotein translocase, YajC subunit. | Preprotein translocase, SecG subunit; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | 0.983 |
Mvan_2582 | Mvan_6075 | Mvan_2582 | Mvan_6075 | TIGRFAM: preprotein translocase, YajC subunit; PFAM: YajC family protein; KEGG: mmc:Mmcs_2275 preprotein translocase, YajC subunit. | PFAM: 60 kDa inner membrane insertion protein; KEGG: mmc:Mmcs_5410 60 kDa inner membrane insertion protein. | 0.940 |
Mvan_2582 | ffh | Mvan_2582 | Mvan_2181 | TIGRFAM: preprotein translocase, YajC subunit; PFAM: YajC family protein; KEGG: mmc:Mmcs_2275 preprotein translocase, YajC subunit. | Signal recognition particle subunit FFH/SRP54 (srp54); Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. | 0.968 |
Mvan_2582 | ftsY | Mvan_2582 | Mvan_2177 | TIGRFAM: preprotein translocase, YajC subunit; PFAM: YajC family protein; KEGG: mmc:Mmcs_2275 preprotein translocase, YajC subunit. | Signal recognition particle-docking protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). | 0.964 |
Mvan_2582 | secA1 | Mvan_2582 | Mvan_1762 | TIGRFAM: preprotein translocase, YajC subunit; PFAM: YajC family protein; KEGG: mmc:Mmcs_2275 preprotein translocase, YajC subunit. | Protein translocase subunit secA; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. | 0.962 |
Mvan_2582 | secA2 | Mvan_2582 | Mvan_1598 | TIGRFAM: preprotein translocase, YajC subunit; PFAM: YajC family protein; KEGG: mmc:Mmcs_2275 preprotein translocase, YajC subunit. | Protein translocase subunit secA; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. | 0.953 |
Mvan_2582 | secA3 | Mvan_2582 | Mvan_3162 | TIGRFAM: preprotein translocase, YajC subunit; PFAM: YajC family protein; KEGG: mmc:Mmcs_2275 preprotein translocase, YajC subunit. | Protein translocase subunit secA; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. | 0.978 |
Mvan_2582 | secE | Mvan_2582 | Mvan_1233 | TIGRFAM: preprotein translocase, YajC subunit; PFAM: YajC family protein; KEGG: mmc:Mmcs_2275 preprotein translocase, YajC subunit. | Protein translocase subunit secE/sec61 gamma; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation. | 0.986 |
Mvan_2582 | secY | Mvan_2582 | Mvan_1347 | TIGRFAM: preprotein translocase, YajC subunit; PFAM: YajC family protein; KEGG: mmc:Mmcs_2275 preprotein translocase, YajC subunit. | Protein translocase subunit secY/sec61 alpha; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. | 0.985 |
Mvan_2706 | Mvan_2582 | Mvan_2706 | Mvan_2582 | Preprotein translocase, SecG subunit; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | TIGRFAM: preprotein translocase, YajC subunit; PFAM: YajC family protein; KEGG: mmc:Mmcs_2275 preprotein translocase, YajC subunit. | 0.983 |
Mvan_2706 | Mvan_6075 | Mvan_2706 | Mvan_6075 | Preprotein translocase, SecG subunit; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | PFAM: 60 kDa inner membrane insertion protein; KEGG: mmc:Mmcs_5410 60 kDa inner membrane insertion protein. | 0.984 |
Mvan_2706 | ffh | Mvan_2706 | Mvan_2181 | Preprotein translocase, SecG subunit; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | Signal recognition particle subunit FFH/SRP54 (srp54); Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. | 0.960 |
Mvan_2706 | ftsY | Mvan_2706 | Mvan_2177 | Preprotein translocase, SecG subunit; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | Signal recognition particle-docking protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). | 0.980 |
Mvan_2706 | secA1 | Mvan_2706 | Mvan_1762 | Preprotein translocase, SecG subunit; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | Protein translocase subunit secA; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. | 0.993 |
Mvan_2706 | secA2 | Mvan_2706 | Mvan_1598 | Preprotein translocase, SecG subunit; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | Protein translocase subunit secA; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. | 0.987 |
Mvan_2706 | secA3 | Mvan_2706 | Mvan_3162 | Preprotein translocase, SecG subunit; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | Protein translocase subunit secA; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. | 0.994 |
Mvan_2706 | secE | Mvan_2706 | Mvan_1233 | Preprotein translocase, SecG subunit; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | Protein translocase subunit secE/sec61 gamma; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation. | 0.999 |
Mvan_2706 | secY | Mvan_2706 | Mvan_1347 | Preprotein translocase, SecG subunit; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | Protein translocase subunit secY/sec61 alpha; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. | 0.998 |
Mvan_6075 | Mvan_2582 | Mvan_6075 | Mvan_2582 | PFAM: 60 kDa inner membrane insertion protein; KEGG: mmc:Mmcs_5410 60 kDa inner membrane insertion protein. | TIGRFAM: preprotein translocase, YajC subunit; PFAM: YajC family protein; KEGG: mmc:Mmcs_2275 preprotein translocase, YajC subunit. | 0.940 |
Mvan_6075 | Mvan_2706 | Mvan_6075 | Mvan_2706 | PFAM: 60 kDa inner membrane insertion protein; KEGG: mmc:Mmcs_5410 60 kDa inner membrane insertion protein. | Preprotein translocase, SecG subunit; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | 0.984 |