Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Mvan_2001PFAM: cytochrome P450; KEGG: mmc:Mmcs_3698 cytochrome P450. (405 aa)    
Predicted Functional Partners:
cyp51
Cytochrome P450; Its precise biological substrate is not known. Catalyzes C14- demethylation of lanosterol, 24,25-dihydrolanosterol and obtusifoliol which is critical for ergosterol biosynthesis. It transforms lanosterol into 4,4'-dimethyl cholesta-8,14,24-triene-3-beta-ol. Belongs to the cytochrome P450 family.
 
  
0.712
Mvan_5160
PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; KR; KEGG: mmc:Mmcs_4581 short-chain dehydrogenase/reductase SDR.
  
  
 0.639
Mvan_3124
PFAM: beta-ketoacyl synthase; acyl transferase domain protein; short-chain dehydrogenase/reductase SDR; phosphopantetheine-binding; KR; KEGG: mbo:Mb2959 phenolpthiocerol synthesis type-I polyketide synthase PpsD.
  
 0.637
Mvan_3126
PFAM: beta-ketoacyl synthase; acyl transferase domain protein; short-chain dehydrogenase/reductase SDR; phosphopantetheine-binding; KR; KEGG: mmc:Mmcs_2835 beta-ketoacyl synthase.
  
 0.637
Mvan_5157
PFAM: aldehyde dehydrogenase; KEGG: mmc:Mmcs_4578 aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
  
 
 0.612
Mvan_5640
Mycolic acid condensase; PFAM: beta-ketoacyl synthase; Thioesterase; acyl transferase domain protein; phosphopantetheine-binding; KEGG: mmc:Mmcs_5010 beta-ketoacyl synthase.
  
 0.578
Mvan_0858
PFAM: cytochrome P450; KEGG: mmc:Mmcs_1717 cytochrome P450.
 
  
 0.575
Mvan_2000
KEGG: mmc:Mmcs_2017 hypothetical protein.
    
  0.563
Mvan_2675
PFAM: AMP-dependent synthetase and ligase; Thioesterase; phosphopantetheine-binding; KEGG: fra:Francci3_1178 AMP-dependent synthetase and ligase.
  
 0.551
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
    
 0.540
Your Current Organism:
Mycolicibacterium vanbaalenii
NCBI taxonomy Id: 350058
Other names: M. vanbaalenii PYR-1, Mycobacterium sp. PYR-1, Mycobacterium vanbaalenii DSM 7251, Mycobacterium vanbaalenii PYR-1, Mycolicibacterium vanbaalenii DSM 7251, Mycolicibacterium vanbaalenii PYR-1
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