Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Mvan_2162PFAM: Alpha/beta hydrolase fold-3 domain protein; KEGG: mmc:Mmcs_1940 alpha/beta hydrolase fold-3. (371 aa)    
Predicted Functional Partners:
Mvan_4116
NAD(P)-dependent nickel-iron dehydrogenase flavin-containing subunit; PFAM: NADH dehydrogenase (ubiquinone), 24 kDa subunit; Respiratory-chain NADH dehydrogenase domain, 51 kDa subunit; KEGG: rme:Rmet_1522 respiratory-chain NADH dehydrogenase domain, 51 kDa subunit.
   
   0.764
Mvan_2163
KEGG: mmc:Mmcs_1941 hypothetical protein.
       0.704
Mvan_2164
PFAM: Vitamin K epoxide reductase; KEGG: mmc:Mmcs_1942 vitamin K epoxide reductase.
       0.704
Mvan_2161
PFAM: aldo/keto reductase; KEGG: mmc:Mmcs_1938 2,5-didehydrogluconate reductase.
     
 0.577
Mvan_2165
Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.
  
  
 0.517
Mvan_1822
PFAM: Alpha/beta hydrolase fold-3 domain protein; KEGG: mbo:Mb3124c PE-PGRS family protein, probably triacylglycerol lipase (esterase/lipase) (triglyceride lipase) (tributyrase).
  
   
 0.511
Mvan_3578
KEGG: mmc:Mmcs_3312 hypothetical protein.
   
 0.504
Mvan_0231
PFAM: Alpha/beta hydrolase fold-3 domain protein; KEGG: mmc:Mmcs_0204 LipO.
  
   
0.479
Mvan_3124
PFAM: beta-ketoacyl synthase; acyl transferase domain protein; short-chain dehydrogenase/reductase SDR; phosphopantetheine-binding; KR; KEGG: mbo:Mb2959 phenolpthiocerol synthesis type-I polyketide synthase PpsD.
  
 
 0.477
Mvan_3126
PFAM: beta-ketoacyl synthase; acyl transferase domain protein; short-chain dehydrogenase/reductase SDR; phosphopantetheine-binding; KR; KEGG: mmc:Mmcs_2835 beta-ketoacyl synthase.
  
 
 0.477
Your Current Organism:
Mycolicibacterium vanbaalenii
NCBI taxonomy Id: 350058
Other names: M. vanbaalenii PYR-1, Mycobacterium sp. PYR-1, Mycobacterium vanbaalenii DSM 7251, Mycobacterium vanbaalenii PYR-1, Mycolicibacterium vanbaalenii DSM 7251, Mycolicibacterium vanbaalenii PYR-1
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