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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hypAHydrogenase expression/synthesis, HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. (132 aa)    
Predicted Functional Partners:
Mvan_2357
TIGRFAM: hydrogenase accessory protein HypB; PFAM: cobalamin synthesis protein, P47K; KEGG: cdi:DIP0671 putative hydrogenase nickel incorporation protein.
 
 
 0.978
Mvan_2366
Hydrogen:quinone oxidoreductase; PFAM: nickel-dependent hydrogenase, large subunit; KEGG: fra:Francci3_1076 hydrogen:quinone oxidoreductase.
 
 
 0.918
Mvan_2417
TIGRFAM: hydrogenase accessory protein HypB; PFAM: cobalamin synthesis protein, P47K; KEGG: mmc:Mmcs_2145 hydrogenase accessory protein HypB.
 
 
 0.908
Mvan_2361
TIGRFAM: hydrogenase expression/formation protein HypD; PFAM: hydrogenase formation HypD protein; KEGG: fra:Francci3_1070 hydrogenase expression/formation protein HypD.
 
  
 0.872
Mvan_2359
TIGRFAM: [NiFe] hydrogenase maturation protein HypF; PFAM: acylphosphatase; SUA5/yciO/yrdC, N-terminal domain; zinc finger, HypF domain protein; KEGG: fra:Francci3_1072 (NiFe) hydrogenase maturation protein HypF; Belongs to the carbamoyltransferase HypF family.
 
   
 0.852
Mvan_2362
TIGRFAM: hydrogenase expression/formation protein HypE; PFAM: AIR synthase related protein; AIR synthase related protein domain protein; KEGG: fra:Francci3_1069 hydrogenase expression/formation protein HypE.
 
  
 0.852
Mvan_2408
TIGRFAM: hydrogenase assembly chaperone hypC/hupF; PFAM: hydrogenase expression/formation protein (HUPF/HYPC); KEGG: mmc:Mmcs_2137 hydrogenase assembly chaperone HypC/HupF.
 
  
 0.826
Mvan_2360
TIGRFAM: hydrogenase assembly chaperone hypC/hupF; PFAM: hydrogenase expression/formation protein (HUPF/HYPC); KEGG: fra:Francci3_1071 hydrogenase assembly chaperone HypC/HupF.
 
  
 0.768
ureG
Urease accessory protein UreG; Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
  
 
 0.755
Mvan_2405
TIGRFAM: hydrogenase expression/formation protein HypD; PFAM: hydrogenase formation HypD protein; KEGG: mmc:Mmcs_2134 hydrogenase expression/formation protein HypD.
 
  
 0.748
Your Current Organism:
Mycolicibacterium vanbaalenii
NCBI taxonomy Id: 350058
Other names: M. vanbaalenii PYR-1, Mycobacterium sp. PYR-1, Mycobacterium vanbaalenii DSM 7251, Mycobacterium vanbaalenii PYR-1, Mycolicibacterium vanbaalenii DSM 7251, Mycolicibacterium vanbaalenii PYR-1
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