| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Mvan_0639 | Mvan_4110 | Mvan_0639 | Mvan_4110 | PFAM: globin; oxidoreductase FAD/NAD(P)-binding domain protein; Oxidoreductase FAD-binding domain protein; KEGG: mmc:Mmcs_0470 oxidoreductase FAD-binding region; Belongs to the globin family. | Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate. | 0.947 |
| Mvan_0639 | carA | Mvan_0639 | Mvan_2663 | PFAM: globin; oxidoreductase FAD/NAD(P)-binding domain protein; Oxidoreductase FAD-binding domain protein; KEGG: mmc:Mmcs_0470 oxidoreductase FAD-binding region; Belongs to the globin family. | KEGG: mpa:MAP1118 carbamoyl-phosphate synthase small chain; TIGRFAM: carbamoyl-phosphate synthase, small subunit; PFAM: glutamine amidotransferase class-I; Carbamoyl-phosphate synthase, small chain; Belongs to the CarA family. | 0.846 |
| Mvan_0639 | carB | Mvan_0639 | Mvan_2664 | PFAM: globin; oxidoreductase FAD/NAD(P)-binding domain protein; Oxidoreductase FAD-binding domain protein; KEGG: mmc:Mmcs_0470 oxidoreductase FAD-binding region; Belongs to the globin family. | TIGRFAM: carbamoyl-phosphate synthase, large subunit; PFAM: protein of unknown function DUF201; Carbamoyl-phosphate synthase L chain, ATP-binding; Carbamoyl-phosphate synthetase large chain, oligomerisation; Carbamoyl-phosphate synthetase large chain domain protein; MGS domain protein; RimK domain protein ATP-grasp; KEGG: mmc:Mmcs_2367 carbamoyl-phosphate synthase, large subunit. | 0.857 |
| Mvan_0639 | pyrC | Mvan_0639 | Mvan_2661 | PFAM: globin; oxidoreductase FAD/NAD(P)-binding domain protein; Oxidoreductase FAD-binding domain protein; KEGG: mmc:Mmcs_0470 oxidoreductase FAD-binding region; Belongs to the globin family. | Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | 0.818 |
| Mvan_0639 | pyrD | Mvan_0639 | Mvan_3487 | PFAM: globin; oxidoreductase FAD/NAD(P)-binding domain protein; Oxidoreductase FAD-binding domain protein; KEGG: mmc:Mmcs_0470 oxidoreductase FAD-binding region; Belongs to the globin family. | Dihydroorotate oxidase A; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | 0.947 |
| Mvan_0639 | pyrE | Mvan_0639 | Mvan_5738 | PFAM: globin; oxidoreductase FAD/NAD(P)-binding domain protein; Oxidoreductase FAD-binding domain protein; KEGG: mmc:Mmcs_0470 oxidoreductase FAD-binding region; Belongs to the globin family. | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.807 |
| Mvan_0639 | pyrF | Mvan_0639 | Mvan_2665 | PFAM: globin; oxidoreductase FAD/NAD(P)-binding domain protein; Oxidoreductase FAD-binding domain protein; KEGG: mmc:Mmcs_0470 oxidoreductase FAD-binding region; Belongs to the globin family. | TIGRFAM: orotidine 5'-phosphate decarboxylase; PFAM: Orotidine 5'-phosphate decarboxylase; KEGG: mpa:MAP1120 orotidine 5'-phosphate decarboxylase; Belongs to the OMP decarboxylase family. Type 2 subfamily. | 0.826 |
| Mvan_3485 | Mvan_3486 | Mvan_3485 | Mvan_3486 | PFAM: SMP-30/Gluconolaconase/LRE domain protein; KEGG: mmc:Mmcs_3160 lipoprotein, putative. | KEGG: mmc:Mmcs_3161 hypothetical protein. | 0.904 |
| Mvan_3485 | pyrD | Mvan_3485 | Mvan_3487 | PFAM: SMP-30/Gluconolaconase/LRE domain protein; KEGG: mmc:Mmcs_3160 lipoprotein, putative. | Dihydroorotate oxidase A; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | 0.866 |
| Mvan_3486 | Mvan_3485 | Mvan_3486 | Mvan_3485 | KEGG: mmc:Mmcs_3161 hypothetical protein. | PFAM: SMP-30/Gluconolaconase/LRE domain protein; KEGG: mmc:Mmcs_3160 lipoprotein, putative. | 0.904 |
| Mvan_3486 | pyrD | Mvan_3486 | Mvan_3487 | KEGG: mmc:Mmcs_3161 hypothetical protein. | Dihydroorotate oxidase A; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | 0.866 |
| Mvan_4110 | Mvan_0639 | Mvan_4110 | Mvan_0639 | Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate. | PFAM: globin; oxidoreductase FAD/NAD(P)-binding domain protein; Oxidoreductase FAD-binding domain protein; KEGG: mmc:Mmcs_0470 oxidoreductase FAD-binding region; Belongs to the globin family. | 0.947 |
| Mvan_4110 | carA | Mvan_4110 | Mvan_2663 | Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate. | KEGG: mpa:MAP1118 carbamoyl-phosphate synthase small chain; TIGRFAM: carbamoyl-phosphate synthase, small subunit; PFAM: glutamine amidotransferase class-I; Carbamoyl-phosphate synthase, small chain; Belongs to the CarA family. | 0.801 |
| Mvan_4110 | carB | Mvan_4110 | Mvan_2664 | Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate. | TIGRFAM: carbamoyl-phosphate synthase, large subunit; PFAM: protein of unknown function DUF201; Carbamoyl-phosphate synthase L chain, ATP-binding; Carbamoyl-phosphate synthetase large chain, oligomerisation; Carbamoyl-phosphate synthetase large chain domain protein; MGS domain protein; RimK domain protein ATP-grasp; KEGG: mmc:Mmcs_2367 carbamoyl-phosphate synthase, large subunit. | 0.830 |
| Mvan_4110 | pheT | Mvan_4110 | Mvan_3316 | Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate. | TIGRFAM: phenylalanyl-tRNA synthetase, beta subunit; KEGG: mmc:Mmcs_2973 phenylalanyl-tRNA synthetase, beta subunit; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | 0.911 |
| Mvan_4110 | pyrC | Mvan_4110 | Mvan_2661 | Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate. | Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. | 0.984 |
| Mvan_4110 | pyrD | Mvan_4110 | Mvan_3487 | Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate. | Dihydroorotate oxidase A; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | 0.900 |
| Mvan_4110 | pyrE | Mvan_4110 | Mvan_5738 | Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate. | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.976 |
| Mvan_4110 | pyrF | Mvan_4110 | Mvan_2665 | Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate. | TIGRFAM: orotidine 5'-phosphate decarboxylase; PFAM: Orotidine 5'-phosphate decarboxylase; KEGG: mpa:MAP1120 orotidine 5'-phosphate decarboxylase; Belongs to the OMP decarboxylase family. Type 2 subfamily. | 0.832 |
| carA | Mvan_0639 | Mvan_2663 | Mvan_0639 | KEGG: mpa:MAP1118 carbamoyl-phosphate synthase small chain; TIGRFAM: carbamoyl-phosphate synthase, small subunit; PFAM: glutamine amidotransferase class-I; Carbamoyl-phosphate synthase, small chain; Belongs to the CarA family. | PFAM: globin; oxidoreductase FAD/NAD(P)-binding domain protein; Oxidoreductase FAD-binding domain protein; KEGG: mmc:Mmcs_0470 oxidoreductase FAD-binding region; Belongs to the globin family. | 0.846 |