Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Mvan_4012PFAM: Xylose isomerase domain protein TIM barrel; KEGG: psp:PSPPH_2335 AP endonuclease, family 2 superfamily; Belongs to the hyi family. (260 aa)    
Predicted Functional Partners:
Mvan_4011
Monosaccharide ABC transporter substrate-binding protein, CUT2 family; PFAM: periplasmic binding protein/LacI transcriptional regulator; KEGG: sma:SAV7151 putative sugar ABC transporter substrate-binding protein; TC 3.A.1.2.-.
 
   
 0.730
Mvan_4010
Monosaccharide ABC transporter membrane protein, CUT2 family; PFAM: inner-membrane translocator; KEGG: rha:RHA1_ro01346 ABC sugar transporter, permease component; TC 3.A.1.2.-; Belongs to the binding-protein-dependent transport system permease family.
 
   
 0.702
Mvan_4009
Monosaccharide ABC transporter ATP-binding protein, CUT2 family; PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: sco:SCO6259 probable ABC sugar transport ATP binding protein; TC 3.A.1.2.-.
 
   
 0.659
iolG1
Inositol 2-dehydrogenase; Involved in the oxidation of myo-inositol (MI) to 2-keto-myo- inositol (2KMI or 2-inosose).
 
  
 0.654
iolG2
Myo-inositol 2-dehydrogenase; Involved in the oxidation of myo-inositol (MI) to 2-keto-myo- inositol (2KMI or 2-inosose).
 
  
 0.653
Mvan_0386
2-keto-myo-inositol dehydratase; PFAM: Xylose isomerase domain protein TIM barrel; KEGG: sma:SAV5337 putative IolE protein.
 
   
 0.611
Mvan_3966
Monosaccharide ABC transporter substrate-binding protein, CUT2 family; SMART: regulatory protein, LacI; KEGG: sma:SAV7191 putative DNA-binding protein; TC 3.A.1.2.-.
 
   
 0.587
Mvan_4019
3D-(3,5/4)-trihydroxycyclohexane-1,2-dione hydrolase; PFAM: thiamine pyrophosphate enzyme domain protein TPP-binding; thiamine pyrophosphate enzyme, central region; thiamine pyrophosphate enzyme TPP binding domain protein; KEGG: rxy:Rxyl_1718 thiamine pyrophosphate enzyme, central region; Belongs to the TPP enzyme family.
 
     0.555
Mvan_4018
5-deoxyglucuronate isomerase; PFAM: Myo-inositol catabolism IolB domain protein; KEGG: sco:SCO6976 IolB protein.
 
     0.527
Mvan_3969
2-keto-myo-inositol dehydratase; PFAM: Xylose isomerase domain protein TIM barrel; KEGG: pac:PPA0468 putative myo-inositol catabolism protein.
 
   
 0.522
Your Current Organism:
Mycolicibacterium vanbaalenii
NCBI taxonomy Id: 350058
Other names: M. vanbaalenii PYR-1, Mycobacterium sp. PYR-1, Mycobacterium vanbaalenii DSM 7251, Mycobacterium vanbaalenii PYR-1, Mycolicibacterium vanbaalenii DSM 7251, Mycolicibacterium vanbaalenii PYR-1
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