STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Mvan_5004KEGG: mmc:Mmcs_2671 hypothetical protein. (1039 aa)    
Predicted Functional Partners:
Mvan_5897
KEGG: mmc:Mmcs_5342 DNA topoisomerase (ATP-hydrolyzing); PFAM: DNA gyrase, subunit B domain protein; ATP-binding region, ATPase domain protein domain protein; SMART: DNA topoisomerase II.
  
 
 0.728
Mvan_6043
KEGG: mmc:Mmcs_5378 hypothetical protein.
  
     0.643
Mvan_5005
ABC transporter-related protein; PFAM: ABC transporter, transmembrane region; ABC transporter related; SMART: AAA ATPase; KEGG: mmc:Mmcs_4444 ABC transporter related.
  
 
 0.634
Mvan_5006
ABC transporter-related protein; PFAM: ABC transporter, transmembrane region; ABC transporter related; SMART: AAA ATPase; KEGG: mmc:Mmcs_4445 ABC transporter related.
  
 
 0.634
Mvan_5007
ABC transporter-related protein; PFAM: ABC transporter, transmembrane region; ABC transporter related; SMART: AAA ATPase; KEGG: mmc:Mmcs_4446 ABC transporter related.
  
 
 0.634
Mvan_3278
Condensin subunit ScpA; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves.
  
 
 0.584
Mvan_1807
ATP-dependent DNA helicase, Rep family; PFAM: UvrD/REP helicase; HRDC domain protein; KEGG: mmc:Mmcs_1409 UvrD/REP helicase.
  
 
 0.533
gyrB
DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
   
 
 0.507
Mvan_5008
PFAM: Ion transport protein; Ion transport 2 domain protein,; KEGG: mmc:Mmcs_4447 ion transport 2.
  
  
 0.494
Mvan_4861
PFAM: glycoside hydrolase, family 8; KEGG: ade:Adeh_2031 glycosyl transferase, family 2.
 
  
 0.493
Your Current Organism:
Mycolicibacterium vanbaalenii
NCBI taxonomy Id: 350058
Other names: M. vanbaalenii PYR-1, Mycobacterium sp. PYR-1, Mycobacterium vanbaalenii DSM 7251, Mycobacterium vanbaalenii PYR-1, Mycolicibacterium vanbaalenii DSM 7251, Mycolicibacterium vanbaalenii PYR-1
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