Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Clos_0010RNA polymerase, sigma 28 subunit, FliA/WhiG family; TIGRFAM: RNA polymerase sigma-70; RNA polymerase sigma-B/F/G type; PFAM: sigma-70 region 3 domain protein; sigma-70 region 2 domain protein; sigma-70 region 4 domain protein; KEGG: amt:Amet_0010 phage transcriptional regulator, RinA family; Belongs to the sigma-70 factor family. (270 aa)    
Predicted Functional Partners:
Clos_0008
Anti-sigma-factor antagonist; TIGRFAM: anti-anti-sigma factor; PFAM: Sulfate transporter/antisigma-factor antagonist STAS; KEGG: amt:Amet_0008 anti-sigma-factor antagonist.
 
 
 0.978
Clos_0009
KEGG: amt:Amet_0009 putative anti-sigma regulatory factor, serine/threonine protein kinase.
 
 
 0.969
Clos_2523
KEGG: cth:Cthe_2246 anti-sigma-28 factor, FlgM.
  
 
 0.882
spoIIAB
Putative anti-sigma regulatory factor, serine/threonine protein kinase; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.
  
 
 0.812
Clos_1796
Anti-sigma-factor antagonist; TIGRFAM: anti-anti-sigma factor; Anti-sigma F factor antagonist; PFAM: Sulfate transporter/antisigma-factor antagonist STAS; KEGG: cpr:CPR_2022 anti-sigma F factor antagonist; Belongs to the anti-sigma-factor antagonist family.
 
  
 0.799
Clos_1494
CheC, inhibitor of MCP methylation / FliN fusion protein; TIGRFAM: flagellar motor switch protein FliN; PFAM: surface presentation of antigens (SPOA) protein; CheC domain protein; KEGG: cth:Cthe_0478 CheC, inhibitor of MCP methylation.
  
  
 0.781
Clos_1960
PFAM: response regulator receiver; CheW domain protein; KEGG: bha:BH2262 modulation of CheA activity in response to attractants (chemotaxis protein).
  
  
 0.754
flgK
TIGRFAM: flagellar hook-associated protein FlgK; PFAM: flagellar basal body rod protein; protein of unknown function DUF1078 domain protein; KEGG: cth:Cthe_2243 flagellar hook-associated protein FlgK.
 
  
 0.732
Clos_1477
TIGRFAM: flagellar basal-body rod protein FlgC; PFAM: flagellar basal body rod protein; protein of unknown function DUF1078 domain protein; KEGG: cth:Cthe_0463 flagellar basal-body rod protein FlgC.
  
 
 0.731
Clos_1476
Flagellar basal-body rod protein FlgB; Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
  
 
 0.711
Your Current Organism:
Alkaliphilus oremlandii
NCBI taxonomy Id: 350688
Other names: A. oremlandii OhILAs, Alkaliphilus oremlandii OhILAs, Alkaliphilus oremlandii str. OhILAs, Alkaliphilus oremlandii strain OhILAs, Clostridium oremlandii OhILAs, Clostridium sp. OhILAs
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