STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sucCsuccinyl-CoA synthetase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (386 aa)    
Predicted Functional Partners:
sucD
succinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
 0.999
Clos_1037
TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: biotin/lipoyl attachment domain-containing protein; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region; KEGG: ctc:CTC02047 dihydrolipoamide dehydrogenase.
  
 
 0.976
Clos_0237
PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; pyruvate ferredoxin/flavodoxin oxidoreductase; pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: amt:Amet_4657 pyruvate flavodoxin/ferredoxin oxidoreductase domain protein.
  
 
 0.971
Clos_1953
PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; pyruvate ferredoxin/flavodoxin oxidoreductase; pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: cbo:CBO1192 pyruvate-flavodoxin oxidoreductase.
  
 
 0.961
Clos_0390
KEGG: fnu:FN0050 fumarate reductase flavoprotein subunit; TIGRFAM: flavocytochrome c; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; HI0933 family protein; FAD dependent oxidoreductase; FMN-binding domain protein; FAD-dependent pyridine nucleotide-disulphide oxidoreductase.
  
 0.957
Clos_0588
PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; HI0933 family protein; FAD dependent oxidoreductase; FMN-binding domain protein; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: ctc:CTC00811 fumarate reductase flavoprotein subunit precursor.
  
 0.957
Clos_2307
PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; FAD dependent oxidoreductase; FMN-binding domain protein; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: ctc:CTC00811 fumarate reductase flavoprotein subunit precursor.
  
 0.957
Clos_2710
PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; HI0933 family protein; FAD dependent oxidoreductase; FMN-binding domain protein; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: ctc:CTC00811 fumarate reductase flavoprotein subunit precursor.
  
 0.957
Clos_0435
PFAM: acetyl-CoA hydrolase/transferase; KEGG: cdf:CD2343 succinyl-CoA:coenzyme A transferase.
   
 0.939
Clos_0871
PFAM: FdrA family protein; KEGG: mta:Moth_2122 FdrA.
  
 0.934
Your Current Organism:
Alkaliphilus oremlandii
NCBI taxonomy Id: 350688
Other names: A. oremlandii OhILAs, Alkaliphilus oremlandii OhILAs, Alkaliphilus oremlandii str. OhILAs, Alkaliphilus oremlandii strain OhILAs, Clostridium oremlandii OhILAs, Clostridium sp. OhILAs
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