Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
Clos_0809KEGG: tde:TDE2415 hypothetical protein. (186 aa)    
Predicted Functional Partners:
Clos_0810
KEGG: tde:TDE2415 hypothetical protein.
 
    
0.868
Clos_0953
KEGG: cbo:CBO1255 component of glycine reductase complex.
  
     0.635
Clos_0811
KEGG: cth:Cthe_1483 hypothetical protein.
       0.563
Clos_0808
PFAM: Ethanolamine utilisation EutQ family protein; KEGG: efa:EF1617 hypothetical protein.
       0.550
Clos_0956
PFAM: Glycine/sarcosine/betaine reductase complex protein B alpha and beta subunits; KEGG: cdf:CD2354 glycine reductase complex component B alpha and beta subunits.
  
     0.548
Clos_0960
Glycine reductase; PFAM: fatty acid synthesis plsX protein; KEGG: cbo:CBO1264 glycine/sarcosine/betaine reductase complex component C alpha subunit.
 
     0.544
Clos_0959
Sarcosine reductase; PFAM: 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III; KEGG: cbo:CBO1263 glycine/sarcosine/betaine reductase complex component C beta subunit.
  
     0.539
grdA
Glycine reductase; In the first step of glycine, betaine and sarcosine reductases, the substrate is bound to component PB via a Schiff base intermediate. Then the PB-activated substrate is nucleophilically attacked by the selenol anion of component PA to transform it to a carboxymethylated selenoether and the respective amine. By action of component PC, acetyl phosphate is formed, leaving component PA in its oxidized state. Finally component PA becomes reduced by the thioredoxin system to start a new catalytic cycle of reductive deamination.
  
     0.518
Clos_0958
Selenoprotein B, glycine/betaine/sarcosine/D-proline reductase family; KEGG: cdf:CD2351 glycine reductase complex component B gamma subunit; Contains selenocysteine; TIGRFAM: glycine reductase, selenoprotein B; selenoprotein B, glycine/betaine/sarcosine/D-proline reductase family; PFAM: Selenoprotein B glycine/betaine/sarcosine/D-proline reductase.
  
     0.509
Clos_0812
Putative sigma54 specific transcriptional regulator; PFAM: sigma-54 factor interaction domain-containing protein; helix-turn-helix Fis-type; ATPase associated with various cellular activities AAA_5; SMART: AAA ATPase; KEGG: chy:CHY_1254 sigma-54 dependent transcriptional regulator.
       0.471
Your Current Organism:
Alkaliphilus oremlandii
NCBI taxonomy Id: 350688
Other names: A. oremlandii OhILAs, Alkaliphilus oremlandii OhILAs, Alkaliphilus oremlandii str. OhILAs, Alkaliphilus oremlandii strain OhILAs, Clostridium oremlandii OhILAs, Clostridium sp. OhILAs
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