node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Clos_0323 | Clos_1019 | Clos_0323 | Clos_1019 | PFAM: anaerobic cobalt chelatase; KEGG: cdf:CD3422 sirohydrochlorin cobaltochelatase. | KEGG: cpr:CPR_1236 precorrin-4 C11-methyltransferase; TIGRFAM: precorrin-4 C11-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Belongs to the precorrin methyltransferase family. | 0.999 |
Clos_0323 | Clos_1023 | Clos_0323 | Clos_1023 | PFAM: anaerobic cobalt chelatase; KEGG: cdf:CD3422 sirohydrochlorin cobaltochelatase. | PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: tde:TDE2657 precorrin-2 C20-methyltransferase, putative; Belongs to the precorrin methyltransferase family. | 0.992 |
Clos_0323 | Clos_1325 | Clos_0323 | Clos_1325 | PFAM: anaerobic cobalt chelatase; KEGG: cdf:CD3422 sirohydrochlorin cobaltochelatase. | Hypothetical protein. | 0.987 |
Clos_0323 | Clos_1326 | Clos_0323 | Clos_1326 | PFAM: anaerobic cobalt chelatase; KEGG: cdf:CD3422 sirohydrochlorin cobaltochelatase. | TIGRFAM: precorrin-6x reductase; siroheme synthase; PFAM: Precorrin-6x reductase CbiJ/CobK; KEGG: cth:Cthe_2526 precorrin-2 oxidase / ferrochelatase. | 0.999 |
Clos_0323 | Clos_1328 | Clos_0323 | Clos_1328 | PFAM: anaerobic cobalt chelatase; KEGG: cdf:CD3422 sirohydrochlorin cobaltochelatase. | TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Uroporphyrinogen III synthase HEM4; KEGG: cth:Cthe_2528 uroporphyrin-III C-methyltransferase. | 0.854 |
Clos_0323 | Clos_1329 | Clos_0323 | Clos_1329 | PFAM: anaerobic cobalt chelatase; KEGG: cdf:CD3422 sirohydrochlorin cobaltochelatase. | Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: cth:Cthe_2529 porphobilinogen synthase; Belongs to the ALAD family. | 0.624 |
Clos_0323 | cbiA | Clos_0323 | Clos_0862 | PFAM: anaerobic cobalt chelatase; KEGG: cdf:CD3422 sirohydrochlorin cobaltochelatase. | Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | 0.929 |
Clos_0323 | hemA | Clos_0323 | Clos_1324 | PFAM: anaerobic cobalt chelatase; KEGG: cdf:CD3422 sirohydrochlorin cobaltochelatase. | Glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.650 |
Clos_0323 | hemC | Clos_0323 | Clos_1327 | PFAM: anaerobic cobalt chelatase; KEGG: cdf:CD3422 sirohydrochlorin cobaltochelatase. | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.706 |
Clos_0323 | hemL | Clos_0323 | Clos_1330 | PFAM: anaerobic cobalt chelatase; KEGG: cdf:CD3422 sirohydrochlorin cobaltochelatase. | TIGRFAM: glutamate-1-semialdehyde-2,1-aminomutase; PFAM: aminotransferase class-III; KEGG: cth:Cthe_2530 glutamate-1-semialdehyde-2,1-aminomutase. | 0.580 |
Clos_1019 | Clos_0323 | Clos_1019 | Clos_0323 | KEGG: cpr:CPR_1236 precorrin-4 C11-methyltransferase; TIGRFAM: precorrin-4 C11-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Belongs to the precorrin methyltransferase family. | PFAM: anaerobic cobalt chelatase; KEGG: cdf:CD3422 sirohydrochlorin cobaltochelatase. | 0.999 |
Clos_1019 | Clos_1023 | Clos_1019 | Clos_1023 | KEGG: cpr:CPR_1236 precorrin-4 C11-methyltransferase; TIGRFAM: precorrin-4 C11-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Belongs to the precorrin methyltransferase family. | PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: tde:TDE2657 precorrin-2 C20-methyltransferase, putative; Belongs to the precorrin methyltransferase family. | 0.986 |
Clos_1019 | Clos_1325 | Clos_1019 | Clos_1325 | KEGG: cpr:CPR_1236 precorrin-4 C11-methyltransferase; TIGRFAM: precorrin-4 C11-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Belongs to the precorrin methyltransferase family. | Hypothetical protein. | 0.764 |
Clos_1019 | Clos_1326 | Clos_1019 | Clos_1326 | KEGG: cpr:CPR_1236 precorrin-4 C11-methyltransferase; TIGRFAM: precorrin-4 C11-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Belongs to the precorrin methyltransferase family. | TIGRFAM: precorrin-6x reductase; siroheme synthase; PFAM: Precorrin-6x reductase CbiJ/CobK; KEGG: cth:Cthe_2526 precorrin-2 oxidase / ferrochelatase. | 0.992 |
Clos_1019 | Clos_1328 | Clos_1019 | Clos_1328 | KEGG: cpr:CPR_1236 precorrin-4 C11-methyltransferase; TIGRFAM: precorrin-4 C11-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Belongs to the precorrin methyltransferase family. | TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Uroporphyrinogen III synthase HEM4; KEGG: cth:Cthe_2528 uroporphyrin-III C-methyltransferase. | 0.775 |
Clos_1019 | Clos_1329 | Clos_1019 | Clos_1329 | KEGG: cpr:CPR_1236 precorrin-4 C11-methyltransferase; TIGRFAM: precorrin-4 C11-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Belongs to the precorrin methyltransferase family. | Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; KEGG: cth:Cthe_2529 porphobilinogen synthase; Belongs to the ALAD family. | 0.676 |
Clos_1019 | cbiA | Clos_1019 | Clos_0862 | KEGG: cpr:CPR_1236 precorrin-4 C11-methyltransferase; TIGRFAM: precorrin-4 C11-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Belongs to the precorrin methyltransferase family. | Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | 0.969 |
Clos_1019 | hemA | Clos_1019 | Clos_1324 | KEGG: cpr:CPR_1236 precorrin-4 C11-methyltransferase; TIGRFAM: precorrin-4 C11-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Belongs to the precorrin methyltransferase family. | Glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). | 0.612 |
Clos_1019 | hemC | Clos_1019 | Clos_1327 | KEGG: cpr:CPR_1236 precorrin-4 C11-methyltransferase; TIGRFAM: precorrin-4 C11-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Belongs to the precorrin methyltransferase family. | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.648 |
Clos_1019 | hemL | Clos_1019 | Clos_1330 | KEGG: cpr:CPR_1236 precorrin-4 C11-methyltransferase; TIGRFAM: precorrin-4 C11-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Belongs to the precorrin methyltransferase family. | TIGRFAM: glutamate-1-semialdehyde-2,1-aminomutase; PFAM: aminotransferase class-III; KEGG: cth:Cthe_2530 glutamate-1-semialdehyde-2,1-aminomutase. | 0.616 |