STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Clos_2010Putative signal-transduction protein with CBS domains; PFAM: CBS domain containing protein; KEGG: bha:BH2605 hypothetical protein. (142 aa)    
Predicted Functional Partners:
Clos_0534
TIGRFAM: GMP synthase, large subunit; PFAM: GMP synthase domain protein; KEGG: ctc:CTC02409 bifunctional GMP synthase/glutamine amidotransferase protein.
     
 0.692
Clos_1257
Protein of unknown function DUF299; Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation.
  
  
 0.659
Clos_1184
PFAM: diacylglycerol kinase catalytic region; KEGG: bca:BCE_0352 conserved hypothetical protein TIGR00147.
 
     0.526
Clos_2011
TIGRFAM: signal peptidase I; PFAM: peptidase S24 S26A and S26B; KEGG: cdf:CD0554 signal peptidase I; Belongs to the peptidase S26 family.
  
    0.506
Clos_0237
PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; pyruvate ferredoxin/flavodoxin oxidoreductase; pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: amt:Amet_4657 pyruvate flavodoxin/ferredoxin oxidoreductase domain protein.
       0.463
Clos_2009
PFAM: phosphoribulokinase/uridine kinase; SMART: AAA ATPase; KEGG: cth:Cthe_0332 phosphoribulokinase/uridine kinase.
       0.433
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
     
 0.416
Your Current Organism:
Alkaliphilus oremlandii
NCBI taxonomy Id: 350688
Other names: A. oremlandii OhILAs, Alkaliphilus oremlandii OhILAs, Alkaliphilus oremlandii str. OhILAs, Alkaliphilus oremlandii strain OhILAs, Clostridium oremlandii OhILAs, Clostridium sp. OhILAs
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