EDM73158.1 protein (Roseobacter sp. AzwK3b) - STRING interaction network

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Score

EDM73158.1

Hypothetical protein; COG2740 Predicted nucleic-acid-binding protein implicated in transcription termination. (210 aa)

Predicted Functional Partners:

infB

0.981

rimP

0.979

nusA

0.973

rplU

0.799

rplW-2

0.788

rpsM

0.774

rpsL

0.738

rplD

0.724

rplF

0.646

fusA

0.641

Your Current Organism:

Roseobacter sp. AzwK3b

NCBI taxonomy Id: 351016
Other names: R. sp. AzwK-3b, Roseobacter sp. AzwK-3b

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
EDM73158.1	fusA	RAZWK3B_03020	RAZWK3B_07174	Hypothetical protein; COG2740 Predicted nucleic-acid-binding protein implicated in transcription termination.	Elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.	0.641
EDM73158.1	infB	RAZWK3B_03020	RAZWK3B_03025	Hypothetical protein; COG2740 Predicted nucleic-acid-binding protein implicated in transcription termination.	Translation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.	0.981
EDM73158.1	nusA	RAZWK3B_03020	RAZWK3B_03015	Hypothetical protein; COG2740 Predicted nucleic-acid-binding protein implicated in transcription termination.	Transcription elongation factor NusA; Participates in both transcription termination and antitermination.	0.973
EDM73158.1	rimP	RAZWK3B_03020	RAZWK3B_03010	Hypothetical protein; COG2740 Predicted nucleic-acid-binding protein implicated in transcription termination.	Hypothetical protein; Required for maturation of 30S ribosomal subunits. Belongs to the RimP family.	0.979
EDM73158.1	rplD	RAZWK3B_03020	RAZWK3B_07194	Hypothetical protein; COG2740 Predicted nucleic-acid-binding protein implicated in transcription termination.	50S ribosomal protein L4; Forms part of the polypeptide exit tunnel.	0.724
EDM73158.1	rplF	RAZWK3B_03020	RAZWK3B_07264	Hypothetical protein; COG2740 Predicted nucleic-acid-binding protein implicated in transcription termination.	50S ribosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family.	0.646
EDM73158.1	rplU	RAZWK3B_03020	RAZWK3B_15163	Hypothetical protein; COG2740 Predicted nucleic-acid-binding protein implicated in transcription termination.	50S ribosomal protein L21/unknown domain fusion protein; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.	0.799
EDM73158.1	rplW-2	RAZWK3B_03020	RAZWK3B_07199	Hypothetical protein; COG2740 Predicted nucleic-acid-binding protein implicated in transcription termination.	Ribosomal protein L25/L23; One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome; Belongs to the universal ribosomal protein uL23 family.	0.788
EDM73158.1	rpsL	RAZWK3B_03020	RAZWK3B_07164	Hypothetical protein; COG2740 Predicted nucleic-acid-binding protein implicated in transcription termination.	30S ribosomal protein S12; Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.	0.738
EDM73158.1	rpsM	RAZWK3B_03020	RAZWK3B_07309	Hypothetical protein; COG2740 Predicted nucleic-acid-binding protein implicated in transcription termination.	30S ribosomal protein S13; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belongs to the universal ribosomal protein uS11 family.	0.774
fusA	EDM73158.1	RAZWK3B_07174	RAZWK3B_03020	Elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.	Hypothetical protein; COG2740 Predicted nucleic-acid-binding protein implicated in transcription termination.	0.641
fusA	infB	RAZWK3B_07174	RAZWK3B_03025	Elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.	Translation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.	0.962
fusA	nusA	RAZWK3B_07174	RAZWK3B_03015	Elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.	Transcription elongation factor NusA; Participates in both transcription termination and antitermination.	0.901
fusA	rplD	RAZWK3B_07174	RAZWK3B_07194	Elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.	50S ribosomal protein L4; Forms part of the polypeptide exit tunnel.	0.998
fusA	rplF	RAZWK3B_07174	RAZWK3B_07264	Elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.	50S ribosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family.	0.999
fusA	rplU	RAZWK3B_07174	RAZWK3B_15163	Elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.	50S ribosomal protein L21/unknown domain fusion protein; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.	0.998
fusA	rplW-2	RAZWK3B_07174	RAZWK3B_07199	Elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.	Ribosomal protein L25/L23; One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome; Belongs to the universal ribosomal protein uL23 family.	0.997
fusA	rpsL	RAZWK3B_07174	RAZWK3B_07164	Elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.	30S ribosomal protein S12; Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.	0.999
fusA	rpsM	RAZWK3B_07174	RAZWK3B_07309	Elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.	30S ribosomal protein S13; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belongs to the universal ribosomal protein uS11 family.	0.998
infB	EDM73158.1	RAZWK3B_03025	RAZWK3B_03020	Translation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.	Hypothetical protein; COG2740 Predicted nucleic-acid-binding protein implicated in transcription termination.	0.981