Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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textmining
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experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
RCIX1132Polyprenyl synthetase; Belongs to the FPP/GGPP synthase family. (289 aa)    
Predicted Functional Partners:
uppS-1
Undecaprenyl pyrophosphate synthetase.
 
 
 0.976
RCIX1254
Putative polyprenyl synthetase; Belongs to the FPP/GGPP synthase family.
  
  
0.924
crtE
Putative farnesyltranstransferase; Belongs to the FPP/GGPP synthase family.
  
  
0.922
menA-1
Putative 1,4-dihydroxy-2-naphthoate octaprenyltransferase.
 
  
 0.853
menA-2
Putative 1,4-dihydroxy-2-naphtoate octaprenyl transferase.
    
 0.831
uppS-2
Putative undecaprenyl pyrophosphate synthetase; Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with geranylgeranyl diphosphate (GGPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30E,34E,38E)-undecaprenyl diphosphate (tritrans,heptacis-UPP). It is probably the precursor of glycosyl carrier lipids.
 
  
 0.785
hmgA-2
3-hydroxy-3-methylglutaryl-coenzyme A reductase; Belongs to the HMG-CoA reductase family.
 
 
 0.683
hmgA
3-hydroxy-3-methylglutaryl-coenzyme a reductase (hmg-coa reductase); Belongs to the HMG-CoA reductase family.
  
 
 0.636
RCIX149
Conserved hypothetical protein; Belongs to the thiolase-like superfamily. UPF0219 family.
  
 
 0.609
RCIX834
Nucleoside-triphosphatase (Ham1-like); Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
 
  
 0.570
Your Current Organism:
Methanocella arvoryzae
NCBI taxonomy Id: 351160
Other names: M. arvoryzae MRE50, Methanocella arvoryzae MRE50, Methanocella arvoryzae str. MRE50, Methanocella arvoryzae strain MRE50, uncultured methanogenic archaeon RC-I, uncultured methanogenic archaeon Rice Cluster I
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