Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
RCIX1140Transcription regulator (Crp family). (258 aa)    
Predicted Functional Partners:
RCIX1141
Conserved hypothetical protein.
 
     0.945
RCIX2278
Putative metallophosphoesterase.
 
     0.816
RCIX1135
Putative ATP-dependent DNA helicase.
 
     0.700
hypF
Putative hydrogenase expression/formation protein (maturation factor).
       0.691
RCIX1860
Conserved hypothetical protein.
  
     0.614
RCIX870
Putative metallo-phosphoesterase.
       0.611
LRC429
Conserved hypothetical protein.
  
     0.599
cofC
Conserved hypothetical protein; Guanylyltransferase that catalyzes the activation of phosphoenolpyruvate (PEP) as enolpyruvoyl-2-diphospho-5'-guanosine, via the condensation of PEP with GTP. It is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor; Belongs to the CofC family.
 
     0.582
RCIX2297
Predicted phosphoesterase (RecJ-like).
  
     0.573
RCIX1045
Conserved hypothetical protein.
  
     0.547
Your Current Organism:
Methanocella arvoryzae
NCBI taxonomy Id: 351160
Other names: M. arvoryzae MRE50, Methanocella arvoryzae MRE50, Methanocella arvoryzae str. MRE50, Methanocella arvoryzae strain MRE50, uncultured methanogenic archaeon RC-I, uncultured methanogenic archaeon Rice Cluster I
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