Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
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[Homology]
Score
prx2-12-cysteine peroxiredoxin. (187 aa)    
Predicted Functional Partners:
dnaK
Chaperonin Hsp70; Acts as a chaperone.
  
 
 0.781
trxB-1
NADPH:thioredoxin reductase (TrxR).
 
 
 0.768
RCIX1654
Glutaredoxin-like protein; Does not function as a glutathione-disulfide oxidoreductase in the presence of glutathione and glutathione reductase. Has low thioredoxin activity in vitro.
  
 0.751
LRC131
Thioredoxin-like protein.
  
 0.746
LRC226
Thioredoxin-like protein.
  
 0.746
trxA-1
Thioredoxin.
  
 0.746
trxA-2
Thioredoxin.
  
 0.746
RCIX360
Thioredoxin-like protein.
  
 0.746
katE
Monofunctional large subunit heme catalase (type I, clade II).
  
 
 0.740
trxB-2
NADPH:thioredoxin reductase (TrxR).
  
 
 0.729
Your Current Organism:
Methanocella arvoryzae
NCBI taxonomy Id: 351160
Other names: M. arvoryzae MRE50, Methanocella arvoryzae MRE50, Methanocella arvoryzae str. MRE50, Methanocella arvoryzae strain MRE50, uncultured methanogenic archaeon RC-I, uncultured methanogenic archaeon Rice Cluster I
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