Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
secFPredicted protein secretion system (SecD/SecF family); Involved in protein export. (320 aa)    
Predicted Functional Partners:
secD
Predicted protein secretion system (SecD/SecF family); Involved in protein export.
 
 0.999
hat
Histone acetyltransferase.
       0.701
RCIX305
dCMP deaminase.
       0.610
RCIX2297
Predicted phosphoesterase (RecJ-like).
 
     0.595
aif2
Translation initiation factor 2; Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2.
 
  
 0.561
atpE
A(1)A(0)-type ATP synthase, subunit E; Produces ATP from ADP in the presence of a proton gradient across the membrane.
 
     0.561
atpF
A(1)A(0)-type ATP synthase, subunit F; Produces ATP from ADP in the presence of a proton gradient across the membrane.
 
     0.561
rpoA2
DNA-directed RNA polymerase, subunit A2; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
 
  
 0.506
mtrC
N(5)-methyltetrahydromethanopterin-coenzyme M methyltransferase, subunit C; Part of a complex that catalyzes the formation of methyl- coenzyme M and tetrahydromethanopterin from coenzyme M and methyl- tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step.
  
    0.496
RCIX1308
Conserved hypothetical protein; Conserved only in haloarcula.
       0.495
Your Current Organism:
Methanocella arvoryzae
NCBI taxonomy Id: 351160
Other names: M. arvoryzae MRE50, Methanocella arvoryzae MRE50, Methanocella arvoryzae str. MRE50, Methanocella arvoryzae strain MRE50, uncultured methanogenic archaeon RC-I, uncultured methanogenic archaeon Rice Cluster I
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