Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
hsdM-2Type I restriction modification system,methyltransferase subunit. (485 aa)    
Predicted Functional Partners:
hsdS-2
Type I restriction modification system,specificity subunit.
 
 0.984
hsdR-2
Type I restriction modification system,restriction subunit.
 
 
 0.975
hsdS-1
Type I restriction modification system,specificity subunit.
 
 
 0.931
hsdS-3
Type I restriction modification system,specificity subunit (fragment).
 
 
 0.907
hsdR-1
Type I restriction modification enzyme,restriction subunit.
  
  
 0.851
RCIX1318
Conserved hypothetical protein.
       0.723
RCIX1319
Conserved hypothetical protein.
       0.501
LRC389
Putative DNA methyltransferase.
  
  
 0.441
Your Current Organism:
Methanocella arvoryzae
NCBI taxonomy Id: 351160
Other names: M. arvoryzae MRE50, Methanocella arvoryzae MRE50, Methanocella arvoryzae str. MRE50, Methanocella arvoryzae strain MRE50, uncultured methanogenic archaeon RC-I, uncultured methanogenic archaeon Rice Cluster I
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