Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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Score
fwdETungsten formylmethanofuran dehydrogenase,subunit E. (208 aa)    
Predicted Functional Partners:
ftr
Formylmethanofuran--tetrahydromethanopterin formyltransferase; Catalyzes the reversible transfer of a formyl group from formylmethanofuran (formyl-MFR) to tetrahydromethanopterin (H(4)MPT) so as to produce 5-formyl tetrahydromethanopterin (5-formyl-H(4)MPT) and methanofuran (MFR); Belongs to the FTR family.
     
 0.908
fdh
NAD-dependent formaldehyde dehydrogenase.
     
  0.900
cbiM-1b
Cobalamin biosynthesis protein, C-terminal fragment.
  
    0.842
cbiM-2
Putative cobalamin biosyntheis protein M.
  
    0.750
cbiM-1a
Cobalamin biosynthesis protein, N-terminal fragment.
  
    0.750
fdhA-1
Formate dehydrogenase, alpha subunit.
  
 
 0.713
fdhA-2
Formate dehydrogenase, alpha subunit.
  
 
 0.713
fdhA-3
Formate dehydrogenase, alpha subunit.
  
 
 0.713
fdhA-4
Formate dehydrogenase, alpha subunit.
  
 
 0.713
fmdE
Putative molybdenum formylmethanofuran dehydrogenase, subunit E.
 
   
 0.712
Your Current Organism:
Methanocella arvoryzae
NCBI taxonomy Id: 351160
Other names: M. arvoryzae MRE50, Methanocella arvoryzae MRE50, Methanocella arvoryzae str. MRE50, Methanocella arvoryzae strain MRE50, uncultured methanogenic archaeon RC-I, uncultured methanogenic archaeon Rice Cluster I
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