Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
RCIX1746Conserved hypothetical protein. (167 aa)    
Predicted Functional Partners:
RCIX1747
Conserved hypothetical protein.
 
     0.856
mcrD-2
Methyl-coenzyme M reductase operon protein D.
  
     0.710
mcrD-1
Methyl-coenzyme M reductase, operon protein D.
  
     0.693
RCIX2003
Conserved hypothetical nitrogenase-related protein.
  
     0.677
LRC174
Conserved hypothetical protein.
  
     0.671
LRC172
Conserved hypothetical protein.
 
     0.658
LRC169
Conserved hypothetical protein.
  
     0.645
mcrG
Methyl-coenzyme M reductase, gamma subunit.
 
     0.640
murD
Putative UDP-N-acetylmuramoylalanine-D-glutamate ligase.
  
     0.631
mcrA
Methyl-coenzyme M reductase, alpha subunit; Component of the methyl-coenzyme M reductase (MCR) I that catalyzes the reductive cleavage of methyl-coenzyme M (CoM-S-CH3 or 2- (methylthio)ethanesulfonate) using coenzyme B (CoB or 7- mercaptoheptanoylthreonine phosphate) as reductant which results in the production of methane and the mixed heterodisulfide of CoB and CoM (CoM-S-S-CoB). This is the final step in methanogenesis.
 
     0.617
Your Current Organism:
Methanocella arvoryzae
NCBI taxonomy Id: 351160
Other names: M. arvoryzae MRE50, Methanocella arvoryzae MRE50, Methanocella arvoryzae str. MRE50, Methanocella arvoryzae strain MRE50, uncultured methanogenic archaeon RC-I, uncultured methanogenic archaeon Rice Cluster I
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