Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
bioYBiotin synthesis protein Y. (175 aa)    
Predicted Functional Partners:
cbiQ-3
Putative ABC-type cobalt import system, permease component.
 
 0.998
cbiO-3
Putative ABC-type cobalt import system, ATPase component.
 
 
 0.997
cbiO-4
Putative ABC-type cobalt import system, ATPase component.
 
 
 0.997
cbiQ-2
Putative ABC-type cobalt import system, permease component.
 
 0.971
birA
biotin--(acetyl-CoA-carboxylase) synthetase.
 
   
 0.941
cbiO-2
Putative ABC-type cobalt import system, ATPase component.
 
 
 
 0.780
LRC577
Putative ABC-type cobalt transport system,permease coponent.
  
 
 0.776
cbiQ-1
Putative ABC-type cobalt import system, permease component.
  
 
 0.776
RCIX1775
ABC-type transport system, ATPase component.
 
 
 
 0.769
LRC578
Putative ABC-type cobalt transport system, ATPase component.
   
 
 0.739
Your Current Organism:
Methanocella arvoryzae
NCBI taxonomy Id: 351160
Other names: M. arvoryzae MRE50, Methanocella arvoryzae MRE50, Methanocella arvoryzae str. MRE50, Methanocella arvoryzae strain MRE50, uncultured methanogenic archaeon RC-I, uncultured methanogenic archaeon Rice Cluster I
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