Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
pgk-1Phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (404 aa)    
Predicted Functional Partners:
gap
Glyceraldehyde-3-phosphate dehydrogenase.
 
 0.999
tpi
Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
 
 
 0.993
eno
Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
 
 
 0.990
RCIX2675
Predicted phosphoglycerate mutase.
  
 
 0.958
pyk
Pyruvate kinase (pyruvate phosphotransferase); Identical to orf1 of fosmid clone 3D10mr4; Belongs to the pyruvate kinase family.
 
 
 0.949
fbaA
Fructose-bisphosphate aldolase (class II).
  
 
 0.949
gpmA-1
2,3-bisphosphoglycerate-independent phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate.
 
  
 0.934
gpmA-2
2,3-bisphosphoglycerate-independent phosphoglycerate mutase.
    
 0.925
rbcL
Ribulose 1,5-bisphosphate carboxylase (RuBisCO),large subunit.
    
 0.920
pgk-2
3-phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family.
  
  
 
0.909
Your Current Organism:
Methanocella arvoryzae
NCBI taxonomy Id: 351160
Other names: M. arvoryzae MRE50, Methanocella arvoryzae MRE50, Methanocella arvoryzae str. MRE50, Methanocella arvoryzae strain MRE50, uncultured methanogenic archaeon RC-I, uncultured methanogenic archaeon Rice Cluster I
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