Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
leuA-32-isopropylmalate synthase. (468 aa)    
Predicted Functional Partners:
pycA
Putative pyruvate carboxylase, subunit A.
  
 
 0.918
pdhC
Pyruvate dehydrogenase complex E2,dihydrolipoamide acetyltransferase.
   
 0.917
porA-1
Pyruvate:ferredoxin oxidoreductase, alpha subunit.
  
 
 0.914
porB-1
Pyruvate:ferredoxin oxidoreductase, beta subunit.
  
 
 0.914
porB-2
Pyruvate:ferredoxin oxidoreductase, beta subunit.
  
 
 0.914
porA-2
Pyruvate:ferredoxin oxidoreductase, alpha subunit.
  
 
 0.914
porC-1
Pyruvate:ferredoxin oxidoreductase, gamma subunit.
  
 
 0.910
porC-2
Pyruvate:ferredoxin oxidoreductase, gamma subunit.
  
 
 0.910
pycB
Pyruvate carboxylase, subunit B.
    
 0.909
porD-1
Pyruvate:ferredoxin oxidoreductase, delta subunit.
    
 0.903
Your Current Organism:
Methanocella arvoryzae
NCBI taxonomy Id: 351160
Other names: M. arvoryzae MRE50, Methanocella arvoryzae MRE50, Methanocella arvoryzae str. MRE50, Methanocella arvoryzae strain MRE50, uncultured methanogenic archaeon RC-I, uncultured methanogenic archaeon Rice Cluster I
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