Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
RCIX1838Conserved hypothetical protein. (128 aa)    
Predicted Functional Partners:
LRC169
Conserved hypothetical protein.
 
    0.921
LRC168
Conserved hypothetical protein.
 
     0.693
mcrD-1
Methyl-coenzyme M reductase, operon protein D.
  
     0.684
mcrC
Methyl-coenzyme M reductase, operon protein C.
 
     0.673
RCIX1837
Conserved hypothetical protein.
 
    
0.669
mcrD-2
Methyl-coenzyme M reductase operon protein D.
  
     0.649
LRC174
Conserved hypothetical protein.
 
     0.637
mtrD
N(5)-methyltetrahydromethanopterin-coenzyme M methyltransferase, subunit D; Part of a complex that catalyzes the formation of methyl- coenzyme M and tetrahydromethanopterin from coenzyme M and methyl- tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step.
  
     0.636
mtrE
N(5)-methyltetrahydromethanopterin-coenzyme M methyltransferase, subunit E; Part of a complex that catalyzes the formation of methyl- coenzyme M and tetrahydromethanopterin from coenzyme M and methyl- tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step.
  
     0.634
LRC180
Conserved hypothetical protein.
  
     0.632
Your Current Organism:
Methanocella arvoryzae
NCBI taxonomy Id: 351160
Other names: M. arvoryzae MRE50, Methanocella arvoryzae MRE50, Methanocella arvoryzae str. MRE50, Methanocella arvoryzae strain MRE50, uncultured methanogenic archaeon RC-I, uncultured methanogenic archaeon Rice Cluster I
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