STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
vhtDPutative coenzyme F420-nonreducing hydrogenase,subunit D (maturation factor). (153 aa)    
Predicted Functional Partners:
vhtG
F420-nonreducing hydrogenase (membrane-bound),small subunit.
 
  
 0.868
vhtA
F420-nonreducing hydrogenase (membrane-bound),large subunit; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.
 
  
 0.864
pyrH
Putative uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP.
       0.767
hypF
Putative hydrogenase expression/formation protein (maturation factor).
 
   
 0.725
hypD
Hydrogenase expression/formation protein (maturation factor).
 
   
 0.717
hypE
Hydrogenase expression/formation protein (maturation factor).
 
   
 0.701
frhA-1
Coenzyme F420-reducing hydrogenase, alpha subunit; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.
 
  
 0.698
frhA-2
Coenzyme F420-reducing hydrogenase, alpha subunit; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.
 
  
 0.695
ileS
isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
   
   0.624
hypB
Hydrogenase expression/formation protein (maturation factor).
 
  
 0.588
Your Current Organism:
Methanocella arvoryzae
NCBI taxonomy Id: 351160
Other names: M. arvoryzae MRE50, Methanocella arvoryzae MRE50, Methanocella arvoryzae str. MRE50, Methanocella arvoryzae strain MRE50, uncultured methanogenic archaeon RC-I, uncultured methanogenic archaeon Rice Cluster I
Server load: low (34%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.