| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| deoA | pyrF | RCIX1126 | RRC356 | Putative thymidine phosphorylase; Catalyzes the conversion of AMP and phosphate to adenine and ribose 1,5-bisphosphate (R15P). Exhibits phosphorylase activity toward CMP and UMP in addition to AMP. Functions in an archaeal AMP degradation pathway, together with R15P isomerase and RubisCO. Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. Type 2 subfamily. | Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. | 0.919 |
| deoA | pyrH | RCIX1126 | RCIX1856 | Putative thymidine phosphorylase; Catalyzes the conversion of AMP and phosphate to adenine and ribose 1,5-bisphosphate (R15P). Exhibits phosphorylase activity toward CMP and UMP in addition to AMP. Functions in an archaeal AMP degradation pathway, together with R15P isomerase and RubisCO. Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. Type 2 subfamily. | Putative uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | 0.919 |
| deoA | surE | RCIX1126 | RCIX2221 | Putative thymidine phosphorylase; Catalyzes the conversion of AMP and phosphate to adenine and ribose 1,5-bisphosphate (R15P). Exhibits phosphorylase activity toward CMP and UMP in addition to AMP. Functions in an archaeal AMP degradation pathway, together with R15P isomerase and RubisCO. Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. Type 2 subfamily. | Nucleoside 5'-monophosphate phosphohydrolase (survival protein); Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.956 |
| leuD-2 | pyrH | RCIX2645 | RCIX1856 | 3-isopropylmalate dehydratase, small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 2 subfamily. | Putative uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | 0.783 |
| ndk | pyrF | LRC143 | RRC356 | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. | Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. | 0.528 |
| ndk | pyrH | LRC143 | RCIX1856 | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. | Putative uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | 0.945 |
| ndk | rpl1p | LRC143 | LRC26 | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. | 50S ribosomal protein L1P; Binds directly to 23S rRNA. Probably involved in E site tRNA release. | 0.412 |
| ndk | rps10p | LRC143 | LRC366 | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. | 30S ribosomal protein S10P; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family. | 0.989 |
| ndk | rps2p | LRC143 | LRC401 | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. | 30S ribosomal protein S2P; Belongs to the universal ribosomal protein uS2 family. | 0.981 |
| ndk | surE | LRC143 | RCIX2221 | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. | Nucleoside 5'-monophosphate phosphohydrolase (survival protein); Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.444 |
| nusA | pyrH | LRC360 | RCIX1856 | Transcription termination factor NusA; Participates in transcription termination. Belongs to the NusA family. | Putative uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | 0.737 |
| nusA | rpl1p | LRC360 | LRC26 | Transcription termination factor NusA; Participates in transcription termination. Belongs to the NusA family. | 50S ribosomal protein L1P; Binds directly to 23S rRNA. Probably involved in E site tRNA release. | 0.970 |
| nusA | rps10p | LRC360 | LRC366 | Transcription termination factor NusA; Participates in transcription termination. Belongs to the NusA family. | 30S ribosomal protein S10P; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family. | 0.989 |
| nusA | rps2p | LRC360 | LRC401 | Transcription termination factor NusA; Participates in transcription termination. Belongs to the NusA family. | 30S ribosomal protein S2P; Belongs to the universal ribosomal protein uS2 family. | 0.975 |
| pyrF | deoA | RRC356 | RCIX1126 | Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. | Putative thymidine phosphorylase; Catalyzes the conversion of AMP and phosphate to adenine and ribose 1,5-bisphosphate (R15P). Exhibits phosphorylase activity toward CMP and UMP in addition to AMP. Functions in an archaeal AMP degradation pathway, together with R15P isomerase and RubisCO. Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. Type 2 subfamily. | 0.919 |
| pyrF | ndk | RRC356 | LRC143 | Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. | 0.528 |
| pyrF | pyrH | RRC356 | RCIX1856 | Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. | Putative uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | 0.940 |
| pyrF | surE | RRC356 | RCIX2221 | Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. | Nucleoside 5'-monophosphate phosphohydrolase (survival protein); Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.941 |
| pyrH | deoA | RCIX1856 | RCIX1126 | Putative uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | Putative thymidine phosphorylase; Catalyzes the conversion of AMP and phosphate to adenine and ribose 1,5-bisphosphate (R15P). Exhibits phosphorylase activity toward CMP and UMP in addition to AMP. Functions in an archaeal AMP degradation pathway, together with R15P isomerase and RubisCO. Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. Type 2 subfamily. | 0.919 |
| pyrH | leuD-2 | RCIX1856 | RCIX2645 | Putative uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | 3-isopropylmalate dehydratase, small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 2 subfamily. | 0.783 |