Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
echAEch hydrogenase, subunit A. (633 aa)    
Predicted Functional Partners:
RCIX481
Putative hydrogenase membrane component (EchB-like).
 
 
 0.997
echF
Ech hydrogenase, subunit F.
 
 
 0.996
echD
Ech hydrogenase, subunit D.
 
 
 0.994
echB
Ech hydrogenase, subunit B.
   
 0.993
echE
Ech hydrogenase, subunit E.
 
  
 0.970
echC
Ech hydrogenase, subunit C.
 
  
 0.960
RCIX482
Putative hydrogenase 2(4Fe-4S) ferredoxin component (EchF-like).
 
 
 0.943
RCIX2387
Hydrogenase, membrane subunit 4-like protein (HycC-like).
 
 
0.897
RCIX2384
Hydrogenase, membrane subunit 1-like protein (EchA-like).
 
 
0.895
pcm
Putative protein-L-isoaspartate O-methyltransferase; Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.
  
   0.663
Your Current Organism:
Methanocella arvoryzae
NCBI taxonomy Id: 351160
Other names: M. arvoryzae MRE50, Methanocella arvoryzae MRE50, Methanocella arvoryzae str. MRE50, Methanocella arvoryzae strain MRE50, uncultured methanogenic archaeon RC-I, uncultured methanogenic archaeon Rice Cluster I
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