Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
echCEch hydrogenase, subunit C. (157 aa)    
Predicted Functional Partners:
echE
Ech hydrogenase, subunit E.
 
 0.999
echB
Ech hydrogenase, subunit B.
 
 
 0.995
RCIX479
[NiFe]-hydrogenase, large subunit (EchE-like).
 
 0.995
RCIX2383
Hydrogenase, large subunit-like protein (HycE-like).
 
 0.987
echF
Ech hydrogenase, subunit F.
 
 
 0.984
echA
Ech hydrogenase, subunit A.
 
  
 0.960
echD
Ech hydrogenase, subunit D.
 
  
 0.916
RCIX2384
Hydrogenase, membrane subunit 1-like protein (EchA-like).
  
 
 0.903
RCIX2387
Hydrogenase, membrane subunit 4-like protein (HycC-like).
  
 
 0.903
RCIX482
Putative hydrogenase 2(4Fe-4S) ferredoxin component (EchF-like).
 
 
 0.844
Your Current Organism:
Methanocella arvoryzae
NCBI taxonomy Id: 351160
Other names: M. arvoryzae MRE50, Methanocella arvoryzae MRE50, Methanocella arvoryzae str. MRE50, Methanocella arvoryzae strain MRE50, uncultured methanogenic archaeon RC-I, uncultured methanogenic archaeon Rice Cluster I
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