Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
echFEch hydrogenase, subunit F. (150 aa)    
Predicted Functional Partners:
echD
Ech hydrogenase, subunit D.
 
 0.998
echA
Ech hydrogenase, subunit A.
 
 
 0.996
RCIX481
Putative hydrogenase membrane component (EchB-like).
 
 0.994
echB
Ech hydrogenase, subunit B.
 
 
 0.993
echE
Ech hydrogenase, subunit E.
 
 
 0.987
echC
Ech hydrogenase, subunit C.
 
 
 0.984
RCIX557
Predicted oxidoreductase integral membrane component (CooM/NuoL-like).
  
 
 0.932
RCIX2383
Hydrogenase, large subunit-like protein (HycE-like).
 
 
 0.888
RCIX479
[NiFe]-hydrogenase, large subunit (EchE-like).
 
 
 0.861
RCIX483
[NiFe]-hydrogenase, small subunit (EchC-like).
 
 
 0.851
Your Current Organism:
Methanocella arvoryzae
NCBI taxonomy Id: 351160
Other names: M. arvoryzae MRE50, Methanocella arvoryzae MRE50, Methanocella arvoryzae str. MRE50, Methanocella arvoryzae strain MRE50, uncultured methanogenic archaeon RC-I, uncultured methanogenic archaeon Rice Cluster I
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