Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
cysH-1Putative 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase). (627 aa)    
Predicted Functional Partners:
cysC
Putative adenylylsulfate kinase (APS kinase).
 
 0.996
cysH-2
Putative 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase).
  
  
 
0.908
sat
Sulfate adenylyltransferase (sulfurylase).
 
  
 0.835
hisH-2
Imidazole glycerol phosphate synthase, glutamine amidotransferase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
     
 0.811
modB
ABC-type molybdenum import system, permease component.
  
  
 0.799
cysG
uroporphyrin-III C-methyltransferase; Belongs to the precorrin methyltransferase family.
 
  
 0.739
RCIX1981
Hypothetical protein.
  
    0.721
hcp
Prismane protein (hybrid cluster protein); Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
  
  
 0.667
RRC405
Conserved hypothetical protein.
 
 
 
 0.640
RCIX2643
Conserved hypothetical protein.
  
     0.562
Your Current Organism:
Methanocella arvoryzae
NCBI taxonomy Id: 351160
Other names: M. arvoryzae MRE50, Methanocella arvoryzae MRE50, Methanocella arvoryzae str. MRE50, Methanocella arvoryzae strain MRE50, uncultured methanogenic archaeon RC-I, uncultured methanogenic archaeon Rice Cluster I
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