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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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[Homology]
Score
dutPutative dUTP pyrophosphatase. (168 aa)    
Predicted Functional Partners:
tmk-2
Putative thymidylate kinase.
  
 
 0.960
thyA
Putative thymidylate synthase.
 
 
 0.957
ndk
Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
  
 
 0.948
tmk-1
Putative thymidylate kinase.
  
 
 0.933
RCIX305
dCMP deaminase.
    
 0.928
RCIX834
Nucleoside-triphosphatase (Ham1-like); Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
 
 
 0.921
nrdD
Anaerobic ribonucleoside-triphosphate reductase (glycyl-dependent).
    
 0.916
surE
Nucleoside 5'-monophosphate phosphohydrolase (survival protein); Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.
  
 
 0.912
RCIX1987
Conserved hypothetical protein.
       0.791
carB
Carbamoyl-phosphate synthase, large subunit; Belongs to the CarB family.
      
 0.553
Your Current Organism:
Methanocella arvoryzae
NCBI taxonomy Id: 351160
Other names: M. arvoryzae MRE50, Methanocella arvoryzae MRE50, Methanocella arvoryzae str. MRE50, Methanocella arvoryzae strain MRE50, uncultured methanogenic archaeon RC-I, uncultured methanogenic archaeon Rice Cluster I
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