Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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[Homology]
Score
atpBA(1)A(0)-type ATP synthase, subunit B; Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit. (458 aa)    
Predicted Functional Partners:
atpI
A(1)A(0)-type ATP synthase, subunit I; Belongs to the V-ATPase 116 kDa subunit family.
 
 0.999
atpK
A(1)A(0)-type ATP synthase, subunit K.
 
 0.999
atpE
A(1)A(0)-type ATP synthase, subunit E; Produces ATP from ADP in the presence of a proton gradient across the membrane.
  
 0.999
atpC
A(1)A(0)-type ATP synthase, subunit C; Produces ATP from ADP in the presence of a proton gradient across the membrane.
 
 0.999
atpF
A(1)A(0)-type ATP synthase, subunit F; Produces ATP from ADP in the presence of a proton gradient across the membrane.
  
 0.999
atpA
A(1)A(0)-type ATP synthase, subunit A; Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit. Belongs to the ATPase alpha/beta chains family.
 
0.999
atpD
A(1)A(0)-type ATP synthase, subunit D; Produces ATP from ADP in the presence of a proton gradient across the membrane.
 
 0.999
RCIX2024
Hypothetical protein.
  
 
 0.991
fusA
Translation elongation factor 2; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 s [...]
 
  
 0.862
secY
Protein translocase, subunit Y; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.
   
  
 0.760
Your Current Organism:
Methanocella arvoryzae
NCBI taxonomy Id: 351160
Other names: M. arvoryzae MRE50, Methanocella arvoryzae MRE50, Methanocella arvoryzae str. MRE50, Methanocella arvoryzae strain MRE50, uncultured methanogenic archaeon RC-I, uncultured methanogenic archaeon Rice Cluster I
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