Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
gmdGDP-mannose 4,6-dehydratase; Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6- deoxy-D-mannose. (333 aa)    
Predicted Functional Partners:
RCIX363
Putative sugar-phosphate adenylyltransferase.
  
  
 0.922
rfbM
Mannose-1-phosphate guanylyltransferase.
    
 0.914
galE-1
Putative UDP-glucose 4-epimerase.
 
    
0.729
rfbC
dTDP-4-dehydrorhamnose 3,5 epimerase.
     
 0.720
RCIX206
Conserved hypothetical protein.
       0.710
apt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of IMP that is energically less costly than de novo synthesis. Belongs to the purine/pyrimidine phosphoribosyltransferase family. Archaeal HPRT subfamily.
    
   0.693
RCIX207
Predicted Fe-S cluster-binding oxidoreductase.
       0.678
rfbB-1
dTDP-glucose 4,6-dehydratase.
     
0.664
rfbD-1
dTDP-4-dehydrorhamnose reductase.
     
 0.638
RCIX208
Glycosyltransferase (family 2).
  
  
 0.593
Your Current Organism:
Methanocella arvoryzae
NCBI taxonomy Id: 351160
Other names: M. arvoryzae MRE50, Methanocella arvoryzae MRE50, Methanocella arvoryzae str. MRE50, Methanocella arvoryzae strain MRE50, uncultured methanogenic archaeon RC-I, uncultured methanogenic archaeon Rice Cluster I
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