Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
tmk-2Putative thymidylate kinase. (208 aa)    
Predicted Functional Partners:
dut
Putative dUTP pyrophosphatase.
  
 
 0.960
ndk
Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.
    
 0.955
thyA
Putative thymidylate synthase.
  
 
 0.943
RCIX305
dCMP deaminase.
    
 0.930
surE
Nucleoside 5'-monophosphate phosphohydrolase (survival protein); Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.
    
 0.920
tmk-1
Putative thymidylate kinase.
 
  
 
0.910
prx1-1
Putative 1-cysteine peroxiredoxin.
 
 
   0.698
rpl1p
50S ribosomal protein L1P; Binds directly to 23S rRNA. Probably involved in E site tRNA release.
 
 
   0.696
dfp
DNA/pantothenate metabolism flavoprotein.
  
  
 0.694
bcp-2
Peroxiredoxin-like bacterioferritin comigratory protein.
   
   0.656
Your Current Organism:
Methanocella arvoryzae
NCBI taxonomy Id: 351160
Other names: M. arvoryzae MRE50, Methanocella arvoryzae MRE50, Methanocella arvoryzae str. MRE50, Methanocella arvoryzae strain MRE50, uncultured methanogenic archaeon RC-I, uncultured methanogenic archaeon Rice Cluster I
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