Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
fumAFumarate hydratase (fumarase), alpha subunit. (288 aa)    
Predicted Functional Partners:
fumB
Fumarate hydratase (fumarase), beta subunit.
 0.999
LRC216
Predicted fumarate reductase/succinate dehydrogenase Fe-S cluster-binding component (HdrD-like).
    
 0.907
LRC333
Predicted Fe-S cluster-binding oxidoreductase.
    
 0.907
RCIX1755
Fe-S cluster-binding oxidoreductase component (HdrD-like).
    
 0.907
RCIX780
Predicted Fe-S cluster-binding oxidoreductase.
    
 0.907
argH
Argininosuccinate lyase.
    
 0.833
aat-1
Putative aspartate aminotransferase.
    
 0.808
aat-5
Putative aspartate aminotransferase.
    
 0.808
apbA
Putative 2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.
 
     0.645
RCIX1279
Conserved hypothetical protein.
       0.602
Your Current Organism:
Methanocella arvoryzae
NCBI taxonomy Id: 351160
Other names: M. arvoryzae MRE50, Methanocella arvoryzae MRE50, Methanocella arvoryzae str. MRE50, Methanocella arvoryzae strain MRE50, uncultured methanogenic archaeon RC-I, uncultured methanogenic archaeon Rice Cluster I
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