| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| LRC61 | pan-1 | LRC61 | RCIX1184 | Predicted protease (Mov34 family). | 26S proteasome regulatory subunit (proteasome-activating nucleotidase); Belongs to the AAA ATPase family. | 0.952 |
| LRC61 | pan-2 | LRC61 | RCIX2455 | Predicted protease (Mov34 family). | 26s proteasome, regulatory subunit (proteasome-activating nucleotidase); ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C- termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, where [...] | 0.952 |
| LRC61 | psmA | LRC61 | RCIX2121 | Predicted protease (Mov34 family). | 20S proteasome, alpha subunit; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. | 0.930 |
| LRC61 | psmB | LRC61 | RCIX2364 | Predicted protease (Mov34 family). | 20S proteasome, beta subunit; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. | 0.930 |
| LRC61 | rpl40e | LRC61 | RCIX1433 | Predicted protease (Mov34 family). | 50S ribosomal protein L40E; Belongs to the eukaryotic ribosomal protein eL40 family. | 0.975 |
| RCIX2122 | psmA | RCIX2122 | RCIX2121 | Conserved hypothetical protein. | 20S proteasome, alpha subunit; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. | 0.944 |
| RCIX2122 | rpl15e | RCIX2122 | RCIX2117 | Conserved hypothetical protein. | 50S ribosomal protein L15E; Belongs to the eukaryotic ribosomal protein eL15 family. | 0.982 |
| RCIX2122 | rpl37ae | RCIX2122 | RCIX2126 | Conserved hypothetical protein. | 50S ribosomal protein L37AE; Binds to the 23S rRNA. | 0.991 |
| RCIX2122 | rpl40e | RCIX2122 | RCIX1433 | Conserved hypothetical protein. | 50S ribosomal protein L40E; Belongs to the eukaryotic ribosomal protein eL40 family. | 0.943 |
| RCIX2122 | rrp42p | RCIX2122 | RCIX2125 | Conserved hypothetical protein. | Putative exosome complex exonuclease 2; Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Contributes to the structuring of the Rrp41 active site. | 0.874 |
| RRC67 | pan-1 | RRC67 | RCIX1184 | Predicted protease (Mov34 family). | 26S proteasome regulatory subunit (proteasome-activating nucleotidase); Belongs to the AAA ATPase family. | 0.952 |
| RRC67 | pan-2 | RRC67 | RCIX2455 | Predicted protease (Mov34 family). | 26s proteasome, regulatory subunit (proteasome-activating nucleotidase); ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C- termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, where [...] | 0.952 |
| RRC67 | psmA | RRC67 | RCIX2121 | Predicted protease (Mov34 family). | 20S proteasome, alpha subunit; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. | 0.930 |
| RRC67 | psmB | RRC67 | RCIX2364 | Predicted protease (Mov34 family). | 20S proteasome, beta subunit; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. | 0.930 |
| RRC67 | rpl40e | RRC67 | RCIX1433 | Predicted protease (Mov34 family). | 50S ribosomal protein L40E; Belongs to the eukaryotic ribosomal protein eL40 family. | 0.958 |
| pan-1 | LRC61 | RCIX1184 | LRC61 | 26S proteasome regulatory subunit (proteasome-activating nucleotidase); Belongs to the AAA ATPase family. | Predicted protease (Mov34 family). | 0.952 |
| pan-1 | RRC67 | RCIX1184 | RRC67 | 26S proteasome regulatory subunit (proteasome-activating nucleotidase); Belongs to the AAA ATPase family. | Predicted protease (Mov34 family). | 0.952 |
| pan-1 | pan-2 | RCIX1184 | RCIX2455 | 26S proteasome regulatory subunit (proteasome-activating nucleotidase); Belongs to the AAA ATPase family. | 26s proteasome, regulatory subunit (proteasome-activating nucleotidase); ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C- termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, where [...] | 0.904 |
| pan-1 | psmA | RCIX1184 | RCIX2121 | 26S proteasome regulatory subunit (proteasome-activating nucleotidase); Belongs to the AAA ATPase family. | 20S proteasome, alpha subunit; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. | 0.962 |
| pan-1 | psmB | RCIX1184 | RCIX2364 | 26S proteasome regulatory subunit (proteasome-activating nucleotidase); Belongs to the AAA ATPase family. | 20S proteasome, beta subunit; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. | 0.956 |