Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
RCIX2211Putative signal transduction histidine kinase. (471 aa)    
Predicted Functional Partners:
RCIX443
Putative response regulator (CheY-like).
 
 
 0.839
pdhB
Pyruvate dehydrogenase complex E1, transketolase beta subunit.
    
 0.673
RCIX1890
Putative response regulator.
 
 
 0.671
gap
Glyceraldehyde-3-phosphate dehydrogenase.
  
 
 0.610
prsA-1
Ribose-phosphate pyrophosphokinase; Belongs to the ribose-phosphate pyrophosphokinase family.
  
 0.577
prsA-2
Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P).
  
 0.577
RCIX1840
Putative response regulator (CheY-like).
 
 
 
 0.535
pdhC
Pyruvate dehydrogenase complex E2,dihydrolipoamide acetyltransferase.
    
 0.523
RRC476
Putative response regulator (CheY-like).
 
 
 
 0.460
RCIX2212
Hypothetical protein.
       0.449
Your Current Organism:
Methanocella arvoryzae
NCBI taxonomy Id: 351160
Other names: M. arvoryzae MRE50, Methanocella arvoryzae MRE50, Methanocella arvoryzae str. MRE50, Methanocella arvoryzae strain MRE50, uncultured methanogenic archaeon RC-I, uncultured methanogenic archaeon Rice Cluster I
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.