Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
RCIX2213Putative transcription regulator (ArsR family). (253 aa)    
Predicted Functional Partners:
RCIX2214
Hypothetical protein.
       0.746
RCIX207
Predicted Fe-S cluster-binding oxidoreductase.
  
  
 0.621
RCIX313
Predicted redox-active protein (CxxC motif).
  
  
 0.621
RRC361
Conserved hypothetical protein.
  
  
 0.621
mcrD-1
Methyl-coenzyme M reductase, operon protein D.
  
     0.605
LRC172
Conserved hypothetical protein.
  
     0.592
mcrD-2
Methyl-coenzyme M reductase operon protein D.
  
     0.581
RRC168
Hypothetical protein.
 
     0.575
RCIX2193
Predicted transcription regulator (ArsR family).
  
     0.526
RCIX1838
Conserved hypothetical protein.
 
     0.519
Your Current Organism:
Methanocella arvoryzae
NCBI taxonomy Id: 351160
Other names: M. arvoryzae MRE50, Methanocella arvoryzae MRE50, Methanocella arvoryzae str. MRE50, Methanocella arvoryzae strain MRE50, uncultured methanogenic archaeon RC-I, uncultured methanogenic archaeon Rice Cluster I
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