Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
rbcLRibulose 1,5-bisphosphate carboxylase (RuBisCO),large subunit. (412 aa)    
Predicted Functional Partners:
eif2b2
Translation initiation factor 2B, subunit 2; Belongs to the eIF-2B alpha/beta/delta subunits family.
 
  
 0.977
pgk-1
Phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family.
    
 0.920
pgk-2
3-phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family.
    
 0.920
RCIX2610
Putative hydrolase (HAD superfamily).
    
 0.911
gph
Phosphoglycolate phosphatase; Catalyzes the dephosphorylation of 2-phosphoglycolate.
    
 0.902
deoA
Putative thymidine phosphorylase; Catalyzes the conversion of AMP and phosphate to adenine and ribose 1,5-bisphosphate (R15P). Exhibits phosphorylase activity toward CMP and UMP in addition to AMP. Functions in an archaeal AMP degradation pathway, together with R15P isomerase and RubisCO. Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. Type 2 subfamily.
 
   
 0.890
RCIX1101
Conserved hypothetical protein.
   
 
 0.834
eif2b1
Translation initiation factor 2B, subunit 1; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.
 
  
 0.647
RCIX919
L-fuculose-phosphate aldolase.
  
  
 0.633
fbaA
Fructose-bisphosphate aldolase (class II).
 
  
 0.632
Your Current Organism:
Methanocella arvoryzae
NCBI taxonomy Id: 351160
Other names: M. arvoryzae MRE50, Methanocella arvoryzae MRE50, Methanocella arvoryzae str. MRE50, Methanocella arvoryzae strain MRE50, uncultured methanogenic archaeon RC-I, uncultured methanogenic archaeon Rice Cluster I
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