STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mcmPutative DNA replication licensing factor; Belongs to the MCM family. (862 aa)    
Predicted Functional Partners:
cdc6-1
Cell division cycle protein 6; Involved in regulation of DNA replication.
 
 0.980
cdc6-2
Cell division cycle protein 6; Involved in regulation of DNA replication.
 
 0.978
rfcS
Replication factor C (clamp loader), small subunit; Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA; Belongs to the activator 1 small subunits family. RfcS subfamily.
 
 
 0.970
polB-4
DNA-directed DNA polymerase B.
  
 0.943
polB-3
Putative DNA-directed DNA polymerase B.
  
 0.940
polB-1
DNA-directed DNA polymerase B.
  
 0.939
eif2b-2
Translation initiation factor 2, beta subunit; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. Belongs to the eIF-2-beta/eIF-5 family.
 
   
 0.935
RCIX407
Conserved hypothetical protein.
  
 0.935
rfcL
Replication factor C, large subunit; Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA; Belongs to the activator 1 small subunits family. RfcL subfamily.
 
 
 0.931
rpoA1
DNA-directed RNA polymerase, subunit A1; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
 
  
 0.929
Your Current Organism:
Methanocella arvoryzae
NCBI taxonomy Id: 351160
Other names: M. arvoryzae MRE50, Methanocella arvoryzae MRE50, Methanocella arvoryzae str. MRE50, Methanocella arvoryzae strain MRE50, uncultured methanogenic archaeon RC-I, uncultured methanogenic archaeon Rice Cluster I
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.