Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
pflAPutative pyruvate formate-lyase activating enzyme. (340 aa)    
Predicted Functional Partners:
LRC400
Conserved hypothetical protein; Belongs to the MEMO1 family.
     0.914
RCIX292
Conserved hypothetical protein.
 
     0.854
RCIX602
Hypothetical protein.
  
    0.636
RCIX246
Polysaccharide deacetylase, N-terminal fragment.
       0.622
thiL-2
Putative thiamine monophosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family.
       0.622
pflX
Putative pyruvate formate-lyase activating enzyme.
 
   
0.575
RRC49
Putative iron-containing alcohol dehydrogenase.
  
  
 0.565
nrdD
Anaerobic ribonucleoside-triphosphate reductase (glycyl-dependent).
  
  
 0.556
moeA-5
Putative molybdopterin biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate; Belongs to the radical SAM superfamily. MoaA family.
  
  
 0.545
RRC155
Conserved hypothetical protein.
 
     0.441
Your Current Organism:
Methanocella arvoryzae
NCBI taxonomy Id: 351160
Other names: M. arvoryzae MRE50, Methanocella arvoryzae MRE50, Methanocella arvoryzae str. MRE50, Methanocella arvoryzae strain MRE50, uncultured methanogenic archaeon RC-I, uncultured methanogenic archaeon Rice Cluster I
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