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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
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Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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[Homology]
Score
matArchaeal S-adenosylmethionine synthetase. (371 aa)    
Predicted Functional Partners:
metE
Putative methylcobalamin:homocysteine methyltransferase.
  
  
 0.926
metY
O-acetyl-L-homoserine sulfhydrylase.
     
  0.900
dcm
C-5 cytosine-specific DNA methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.
     
  0.900
metK
S-adenosylmethionine synthetase.
     
  0.900
hisG
ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Long subfamily.
  
    0.734
cyaB
Adenylate cyclase.
 
     0.712
hisA-2
Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase.
       0.692
hisB
Putative imidazoleglycerol-phosphate dehydratase.
       0.692
RRC419
Putative DNA-binding protein (translin family).
       0.589
scpB
Putative chromosome segregation/condensation protein B.
       0.563
Your Current Organism:
Methanocella arvoryzae
NCBI taxonomy Id: 351160
Other names: M. arvoryzae MRE50, Methanocella arvoryzae MRE50, Methanocella arvoryzae str. MRE50, Methanocella arvoryzae strain MRE50, uncultured methanogenic archaeon RC-I, uncultured methanogenic archaeon Rice Cluster I
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