Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
RCIX2278Putative metallophosphoesterase. (174 aa)    
Predicted Functional Partners:
RCIX1140
Transcription regulator (Crp family).
 
     0.816
RCIX1141
Conserved hypothetical protein.
       0.786
prx1-2
1-cysteine peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.
 
 
 0.737
RCIX1862
Conserved GTP-binding protein (Ras family).
 
 
 
 0.701
RCIX2110
Conserved hypothetical protein.
 
     0.701
prx2-1
2-cysteine peroxiredoxin.
  
 
 0.696
prx2-2
2-cysteine peroxiredoxin.
  
 
 0.696
prx2-3
Putative 2-cysteine peroxiredoxin.
  
 
 0.696
mcm
Putative DNA replication licensing factor; Belongs to the MCM family.
       0.667
tfb
Transcription initiation factor IIB; Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB).
  
    0.644
Your Current Organism:
Methanocella arvoryzae
NCBI taxonomy Id: 351160
Other names: M. arvoryzae MRE50, Methanocella arvoryzae MRE50, Methanocella arvoryzae str. MRE50, Methanocella arvoryzae strain MRE50, uncultured methanogenic archaeon RC-I, uncultured methanogenic archaeon Rice Cluster I
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