Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
RCIX2300Predicted cation efflux protein. (315 aa)    
Predicted Functional Partners:
RCIX2302
Hypothetical protein.
       0.499
RCIX2724
Putative metallo-beta-lactamase.
  
    0.490
feoB
Fe(II) import system, GTP-binding protein B.
 
   
 0.471
RCIX363
Putative sugar-phosphate adenylyltransferase.
  
  
 0.457
RCIX322
Conserved hypothetical protein.
  
  
 0.452
LRC111
Putative transporter (NRAMP family).
   
 
 0.435
nnrE
Conserved hypothetical protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair o [...]
 
    0.426
RRC285
Hypothetical protein.
 
  
 0.421
RCIX1787
Cation-transporting P-type ATPase.
 
 
 0.408
cadA
Putative Cd(2+)-translocating P-type ATPase.
 
 
 0.406
Your Current Organism:
Methanocella arvoryzae
NCBI taxonomy Id: 351160
Other names: M. arvoryzae MRE50, Methanocella arvoryzae MRE50, Methanocella arvoryzae str. MRE50, Methanocella arvoryzae strain MRE50, uncultured methanogenic archaeon RC-I, uncultured methanogenic archaeon Rice Cluster I
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