Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
apbAPutative 2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. (296 aa)    
Predicted Functional Partners:
RCIX620
Predicted archaea-specific kinase (GHMP-like family).
    
 0.948
zim
N-4 cytosine-specific methyltransferase.
       0.746
fumB
Fumarate hydratase (fumarase), beta subunit.
 
    0.659
fumA
Fumarate hydratase (fumarase), alpha subunit.
 
     0.645
RCIX2331
Hypothetical protein.
       0.636
RCIA88
Predicted 6-O-methylguanine-DNA methyltransferase.
       0.622
RCIX2359
rRNA methyltransferase (SpoU family).
     
 0.622
RCIX860
Conserved hypothetical protein.
 
   
 0.588
hflX
Conserved GTP-binding protein; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
       0.504
dfp
DNA/pantothenate metabolism flavoprotein.
  
  
 0.501
Your Current Organism:
Methanocella arvoryzae
NCBI taxonomy Id: 351160
Other names: M. arvoryzae MRE50, Methanocella arvoryzae MRE50, Methanocella arvoryzae str. MRE50, Methanocella arvoryzae strain MRE50, uncultured methanogenic archaeon RC-I, uncultured methanogenic archaeon Rice Cluster I
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