Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
RCIX2342Conserved hypothetical protein. (332 aa)    
Predicted Functional Partners:
RCIX2341
2(4Fe-4S) ferredoxin-domain protein.
 
     0.986
cdhD
Carbon monoxide dehydrogenase/acetyl-CoA synthase complex, corrinoid small subunit; Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing autotrophic growth from CO(2). Probably maintains the overall quaternary structure of the ACDS complex. Belongs to the CdhD family.
 
 
 0.975
cdhC
Carbon monoxide dehydrogenase/acetyl-CoA synthase complex, beta subunit; Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing autotrophic growth from CO(2). The alpha-epsilon complex generates CO from CO(2), while the beta subunit (this protein) combines the CO with CoA and a methyl group to form acetyl-CoA. The methyl group, which is incorporated into acetyl-CoA, is transferred to the beta subunit by a corrinoid iron-sulfur protein (the gamma-delta complex); Belongs to the CdhC family.
 
 
 0.951
RCIX2343
Putative transcription regulator (AbrB family).
 
     0.936
cdhA
Carbon monoxide dehydrogenase/acetyl-CoA synthase complex, alpha subunit; Part of the ACDS complex that catalyzes the reversible cleavage of acetyl-CoA, allowing autotrophic growth from CO(2). The alpha-epsilon subcomponent functions as a carbon monoxide dehydrogenase.
 
 
 0.884
cooC-2
Putative carbon monoxide dehydrogenase maturation factor (accessory nickel-insertion protein).
 
  
 0.652
cdhB
Carbon monoxide dehydrogenase/acetyl-CoA synthase complex, epsilon subunit.
 
  
 0.638
cooC-1
Putative carbon monoxide dehydrogenase maturation factor (accessory nickel-insertion protein).
 
  
 0.620
cooC-3
Putative carbon monoxide dehydrogenase maturation factor (accessory nickel-insertion protein).
 
  
 0.578
RCIA168
Hypothetical protein.
       0.515
Your Current Organism:
Methanocella arvoryzae
NCBI taxonomy Id: 351160
Other names: M. arvoryzae MRE50, Methanocella arvoryzae MRE50, Methanocella arvoryzae str. MRE50, Methanocella arvoryzae strain MRE50, uncultured methanogenic archaeon RC-I, uncultured methanogenic archaeon Rice Cluster I
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