| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| RCIA88 | RCIX2359 | RCIA88 | RCIX2359 | Predicted 6-O-methylguanine-DNA methyltransferase. | rRNA methyltransferase (SpoU family). | 0.622 |
| RCIA88 | apbA | RCIA88 | RCIX2330 | Predicted 6-O-methylguanine-DNA methyltransferase. | Putative 2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. | 0.622 |
| RCIX2245 | RCIX2359 | RCIX2245 | RCIX2359 | Conserved hypothetical protein. | rRNA methyltransferase (SpoU family). | 0.673 |
| RCIX2245 | rnh | RCIX2245 | RCIX928 | Conserved hypothetical protein. | Ribonuclease H (RNase H); Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. | 0.449 |
| RCIX2353 | RCIX2359 | RCIX2353 | RCIX2359 | Protoporphyrinogen oxidase-related protein (HemK-like). | rRNA methyltransferase (SpoU family). | 0.586 |
| RCIX2359 | RCIA88 | RCIX2359 | RCIA88 | rRNA methyltransferase (SpoU family). | Predicted 6-O-methylguanine-DNA methyltransferase. | 0.622 |
| RCIX2359 | RCIX2245 | RCIX2359 | RCIX2245 | rRNA methyltransferase (SpoU family). | Conserved hypothetical protein. | 0.673 |
| RCIX2359 | RCIX2353 | RCIX2359 | RCIX2353 | rRNA methyltransferase (SpoU family). | Protoporphyrinogen oxidase-related protein (HemK-like). | 0.586 |
| RCIX2359 | RCIX2360 | RCIX2359 | RCIX2360 | rRNA methyltransferase (SpoU family). | Predicted metallophosphoesterase. | 0.603 |
| RCIX2359 | apbA | RCIX2359 | RCIX2330 | rRNA methyltransferase (SpoU family). | Putative 2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. | 0.622 |
| RCIX2359 | ftsJ | RCIX2359 | RCIX2745 | rRNA methyltransferase (SpoU family). | 23S rRNA methyltransferase J; Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit. | 0.582 |
| RCIX2359 | moaC | RCIX2359 | RCIX2358 | rRNA methyltransferase (SpoU family). | Molybdopterin biosynthesis protein C; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family. | 0.791 |
| RCIX2359 | mptE | RCIX2359 | RCIX381 | rRNA methyltransferase (SpoU family). | Conserved hypothetical protein; Catalyzes the transfer of diphosphate from ATP to 6- hydroxymethyl-7,8-dihydropterin (6-HMD), leading to 6-hydroxymethyl- 7,8-dihydropterin diphosphate (6-HMDP); Belongs to the archaeal 6-HMPDK family. | 0.546 |
| RCIX2359 | nnrE | RCIX2359 | RCIX2357 | rRNA methyltransferase (SpoU family). | Conserved hypothetical protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair o [...] | 0.627 |
| RCIX2359 | rnh | RCIX2359 | RCIX928 | rRNA methyltransferase (SpoU family). | Ribonuclease H (RNase H); Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. | 0.555 |
| RCIX2360 | RCIX2359 | RCIX2360 | RCIX2359 | Predicted metallophosphoesterase. | rRNA methyltransferase (SpoU family). | 0.603 |
| RCIX2360 | moaC | RCIX2360 | RCIX2358 | Predicted metallophosphoesterase. | Molybdopterin biosynthesis protein C; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family. | 0.603 |
| RCIX2360 | nnrE | RCIX2360 | RCIX2357 | Predicted metallophosphoesterase. | Conserved hypothetical protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair o [...] | 0.446 |
| apbA | RCIA88 | RCIX2330 | RCIA88 | Putative 2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. | Predicted 6-O-methylguanine-DNA methyltransferase. | 0.622 |
| apbA | RCIX2359 | RCIX2330 | RCIX2359 | Putative 2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. | rRNA methyltransferase (SpoU family). | 0.622 |