Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
psmB20S proteasome, beta subunit; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. (208 aa)    
Predicted Functional Partners:
psmA
20S proteasome, alpha subunit; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation.
 
 
0.966
RCIX2365
mRNA cleavage/polyadenylation specificity factor,100 kD subunit.
 
   
 0.942
pan-1
26S proteasome regulatory subunit (proteasome-activating nucleotidase); Belongs to the AAA ATPase family.
  
 0.922
pan-2
26s proteasome, regulatory subunit (proteasome-activating nucleotidase); ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C- termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, where [...]
  
 0.922
LRC61
Predicted protease (Mov34 family).
   
 0.859
RRC67
Predicted protease (Mov34 family).
   
 0.859
rpl40e
50S ribosomal protein L40E; Belongs to the eukaryotic ribosomal protein eL40 family.
   
 0.835
cdc48-3
Cell division cycle protein 48.
  
 0.716
cdc48-1
Putative cell division cycle protein 48.
  
 0.716
cdc48-2
Cell division cycle protein 48.
  
 0.716
Your Current Organism:
Methanocella arvoryzae
NCBI taxonomy Id: 351160
Other names: M. arvoryzae MRE50, Methanocella arvoryzae MRE50, Methanocella arvoryzae str. MRE50, Methanocella arvoryzae strain MRE50, uncultured methanogenic archaeon RC-I, uncultured methanogenic archaeon Rice Cluster I
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